ATP6V1B2 Antibodies

AND ATP6V1B2 ELISA kits, ATP6V1B2 Proteins

Many biological assays use antibodies to detect ATP6V1B2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ATP6V1B2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ATP6V1B2 antibodies...

We validate the specificity of these antibodies to ATP6V1B2 by testing them on tissues known to express ATP6V1B2 positively and negatively. Browse below to find the ATP6V1B2 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ATP6V1B2 Infographic by Boster Bio

All ATP6V1B2 Products

Product

Figures

Specificity

Applications

Price

Anti-ATP6V1B2 Antibody

Human, Mouse, Rat

$405
Cat # A04927
100ul

ATP6V1B2 (NM_001693) Human Recombinant Protein

$1249
Cat # PROTP21281
20 µg

Anti-ATP6V1B2 Mouse Monoclonal Antibody [Clone ID: OTI1E11]

Human, Mouse, Rat

IHC, WB

$523
Cat # M04927
100 µl

ATP6V1B2 (NM_001693) Human Over-expression Lysate

Human

$628
Cat # LS000526
100 µg

ATP6V1B2 Overview

Facts about V-type proton ATPase subunit B, brain isoform.

ATP6V1B2 3D structure. Source: alphafold

V-type proton ATPase subunit B, brain isoform (ATP6V1B2)

Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.

Gene Information

Human
Gene Name:	ATP6V1B2
Uniprot:	P21281
Entrez:	526

Family

Belongs to:

ATPase alpha/beta chains family

Alternative Names

000 subunit; 56/58kD, isoform 2; ATP6B2ATPase, H+ transporting, lysosomal (vacuolar proton pump), beta polypeptide; ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2; Endomembrane proton pump 58 kDa subunit; H+ transporting two-sector ATPase; HO57ATP6B1B2; vacuolar H+-ATPase 56; Vacuolar proton pump subunit B 2; VATB; V-ATPase B2 subunit; V-ATPase subunit B 2; Vma2; VPP3ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B, isoform 2; V-type proton ATPase subunit B, brain isoform

Molecular Weight

Mass (kDA):
56.501 kDA

Genomic Context


Human

Location:	8p21.3
Sequence:	8; NC_000008.11 (20197375..20226852)

Subcellular Localizations

Endomembrane system; Peripheral membrane protein. Melanosome. Endomembrane. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

Diseases

Epilepsy, Generalized
Metabolic Acidosis
Degenerative Polyarthritis
Endoplasmic Reticulum Stress
Insulin Resistance
Fracture
Nephritis
Pigmented Villonodular Synovitis
Febrile Convulsions
Rheumatoid Arthritis
Spinal Muscular Atrophy
Mucinous Adenocarcinoma

Acidosis
Muscular Atrophy
Schizophrenia
Atrophy
Absence Epilepsy
Tissue Adhesions
Diabetes Mellitus

Interacting Proteins

TCF4

Pathways

Transport
Secretion
Proton Transport
Pathogenesis
Cell Adhesion
Cell Proliferation
Electron Transport
Insulin Secretion
Electron Transport Chain
Immune Response
Oxidative Phosphorylation

Localization
Actin Filament Polymerization
Flight
Respiratory Electron Transport Chain
Vacuolar Transport

PTMs

Phosphorylation

Oxidation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ATP6V1B2

References

PMID: 1373501 by Nelson R.D., et al. Selectively amplified expression of an isoform of the vacuolar H(+)- ATPase 56-kilodalton subunit in renal intercalated cells.

PMID: 7945239 by van Hille B., et al. Heterogeneity of vacuolar H(+)-ATPase: differential expression of two human subunit B isoforms.