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ATP6V1B2 Antibodies
AND ATP6V1B2 ELISA kits, ATP6V1B2 Proteins
Many biological assays use antibodies to detect ATP6V1B2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ATP6V1B2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ATP6V1B2 antibodies...
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ATP6V1B2 Infographic by Boster Bio
All ATP6V1B2 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
IHC, WB
$523
Cat # M04927
100 µl
Cat # M04927
100 µl
ATP6V1B2 Overview
Facts about V-type proton ATPase subunit B, brain isoform.
V-type proton ATPase subunit B, brain isoform (ATP6V1B2)
Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
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Gene Information
| Human | |
|---|---|
| Gene Name: | ATP6V1B2 |
| Uniprot: | P21281 |
| Entrez: | 526 |
Family
| Belongs to: |
|---|
| ATPase alpha/beta chains family |
Alternative Names
000 subunit; 56/58kD, isoform 2; ATP6B2ATPase, H+ transporting, lysosomal (vacuolar proton pump), beta polypeptide; ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2; Endomembrane proton pump 58 kDa subunit; H+ transporting two-sector ATPase; HO57ATP6B1B2; vacuolar H+-ATPase 56; Vacuolar proton pump subunit B 2; VATB; V-ATPase B2 subunit; V-ATPase subunit B 2; Vma2; VPP3ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B, isoform 2; V-type proton ATPase subunit B, brain isoform
Molecular Weight
Mass (kDA):
56.501 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 8p21.3 |
| Sequence: | 8; NC_000008.11 (20197375..20226852) |
Subcellular Localizations
Endomembrane system; Peripheral membrane protein. Melanosome. Endomembrane. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Diseases
- Epilepsy, Generalized
- Metabolic Acidosis
- Degenerative Polyarthritis
- Endoplasmic Reticulum Stress
- Insulin Resistance
- Fracture
- Nephritis
- Pigmented Villonodular Synovitis
- Febrile Convulsions
- Rheumatoid Arthritis
- Spinal Muscular Atrophy
- Mucinous Adenocarcinoma
Interacting Proteins
- TCF4
Pathways
- Transport
- Secretion
- Proton Transport
- Pathogenesis
- Cell Adhesion
- Cell Proliferation
- Electron Transport
- Insulin Secretion
- Electron Transport Chain
- Immune Response
- Oxidative Phosphorylation
PTMs
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ATP6V1B2
bosterbio.com/bosterbio-gene-info-cards/ATP6V1B2
References
PMID: 1373501 by Nelson R.D., et al. Selectively amplified expression of an isoform of the vacuolar H(+)- ATPase 56-kilodalton subunit in renal intercalated cells.
PMID: 7945239 by van Hille B., et al. Heterogeneity of vacuolar H(+)-ATPase: differential expression of two human subunit B isoforms.