ADAM23 Antibodies

AND ADAM23 ELISA kits, ADAM23 Proteins

Many biological assays use antibodies to detect ADAM23, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ADAM23 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ADAM23 antibodies...

We validate the specificity of these antibodies to ADAM23 by testing them on tissues known to express ADAM23 positively and negatively. Browse below to find the ADAM23 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for ADAM23? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the ADAM23 IHC Guide

ADAM23 Infographic by Boster Bio

All ADAM23 Products

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Applications

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Anti-ADAM23 Antibody

Immunohistochemistry (IHC) analyzes of ADAM23 pAb in paraffin-embedded human rectum carcinoma tissue at 1:50,showing strong cytoplasmic staining

Western blot (WB) analysis of ADAM23 polyclonal antibody at 1:500 dilution
Lane1:MCF-7 whole cell lysate
Lane2:Raw264

Human, Mouse

IHC, WB

$405
Cat # A07382
100ul

ADAM23 (NM_003812) Human Over-expression Lysate

Human

$960
Cat # LS008745
20 µg, 100 µg

ADAM23 Overview

Facts about Disintegrin and metalloproteinase domain-containing protein 23.

ADAM23 3D structure. Source: alphafold

Disintegrin and metalloproteinase domain-containing protein 23 (ADAM23)

May play a role in cell-cell and cell-matrix interactions. This is a non-catalytic metalloprotease-like protein.

Gene Information

Human
Gene Name:	ADAM23
Uniprot:	O75077
Entrez:	8745

Family

Belongs to:

No superfamily

Alternative Names

a disintegrin and metalloproteinase domain 23; ADAM metallopeptidase domain 23; ADAM23; disintegrin and metalloproteinase domain-containing protein 23; MDC3; MDC-3; MDC3ADAM 23; MDC-L; Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3

Molecular Weight

Mass (kDA):
91.926 kDA

Genomic Context


Human

Location:	2q33.3
Sequence:	2; NC_000002.12 (206443532..206621127)

Tissue Specificity

Highly expressed in the brain and weakly expressed in the heart. In the brain, expressed prominently in the amygdala, caudate nucleus, hypothalamus, thalamus, cerebral cortex and occipital pole.

Subcellular Localizations

Cell membrane; Single-pass type I membrane protein.; [Isoform Gamma]: Secreted.

Diseases

Neoplasms
Malignant Neoplasms
Tissue Adhesions
Neoplasm Metastasis
Carcinoma
Epilepsy
Stomach Neoplasms
Nervousness
Malignant Neoplasm Of Stomach
Malignant Neoplasm Of Breast
Glioma
Mammary Neoplasms

Tumor Progression
Carcinogenesis
Metastatic Malignant Neoplasm To The Lymph Node
Embryonal Carcinoma
Malignant Paraganglionic Neoplasm
Epilepsies, Partial

Pathways

Methylation
Cell Adhesion
Brain Development
Fertilization
Gene Silencing
Cell Cycle
Dna Methylation
Demethylation
Cell Migration
Developmental Process
Dna Hypermethylation
Proteolysis
Cell Fate Determination

Neurogenesis
Vasculogenesis
Cell Cycle Arrest
System Development
Exocytosis
Myoblast Fusion
Cell-cell Adhesion

PTMs

Methylation
Demethylation

Glycosylation
Reduction

Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ADAM23

References

PMID: 9693107 by Sagane K., et al. Metalloproteinase-like, disintegrin-like, cysteine-rich proteins MDC2 and MDC3: novel human cellular disintegrins highly expressed in the brain.

PMID: 10749942 by Cal S., et al. ADAM 23/MDC3, a human disintegrin that promotes cell adhesion via interaction with the alpha v beta 3 integrin through an RGD- independent mechanism.