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- Table of Contents
B4GALT1 Antibodies
AND B4GALT1 ELISA kits, B4GALT1 Proteins
Many biological assays use antibodies to detect B4GALT1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with B4GALT1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop B4GALT1 antibodies...
Designing a Western blot for B4GALT1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the B4GALT1 Western Blot GuideB4GALT1 Infographic by Boster Bio
All B4GALT1 Products
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B4GALT1 Overview
Facts about Beta-1,4-galactosyltransferase 1.
Beta-1,4-galactosyltransferase 1 (B4GALT1)
The Golgi complex form catalyzes the production of flaxseed from the lactating mammary gland and might also cause the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids. .
Gene Information
| Human | |
|---|---|
| Gene Name: | B4GALT1 |
| Uniprot: | P15291 |
| Entrez: | 2683 |
Family
| Belongs to: |
|---|
| glycosyltransferase 7 family |
Alternative Names
1,4- galactosyltransferase, polypeptide 1; B4GalT1; B4GAL-T1; beta-1,4-galactosyltransferase 1; Beta-1,4-GalTase 1; beta4Gal-T1; betaGlcNAc beta; CDG2D; EC 2.4.1; GGTB2; GGTB2DKFZp686N19253; glycoprotein-4-beta-galactosyltransferase 2; GT1; GTB; lactose synthase; MGC50983; UDP-Gal; UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 1; UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 1
Molecular Weight
Mass (kDA):
43.92 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 9p21.1 |
| Sequence: | 9; NC_000009.12 (33104077..33167336, complement) |
Tissue Specificity
Ubiquitously expressed, but at very low levels in fetal and adult brain.
Subcellular Localizations
[Isoform Long]: Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Cell membrane; Single-pass type II membrane protein. Cell surface. Cell projection, filopodium. Found in trans cisternae of Golgi but is mainly localized at the plasma membrane (PubMed:1714903). B4GALT1 cell surface expression is regulated by UBE2Q1 (By similarity).; [Isoform Short]: Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Found in trans cisternae of Golgi.; [Processed beta-1,4-galactosyltransferase 1]: Secreted. Soluble form found in body fluids.
Diseases
- Malignant Neoplasms
- Malignant Neoplasm Of Breast
- Congenital Disorders Of Glycosylation
- Congenital Disorders
- Neoplasm Metastasis
- Carcinoma
- Inflammation
- Liver Diseases
- Adenoma
- Embryonal Carcinoma
- Inflammatory Bowel Diseases
- Neoplasm Invasiveness
- Intestinal Diseases
Pathways
- Glycosylation
- Localization
- Germinal Center Formation
- Mature B Cell Differentiation
- Cell Proliferation
- Lactation
- Fertilization
- Somitogenesis
- Sex Determination
- Dosage Compensation
- Fucosylation
- Methylation
- Flight
PTMs
- Glycosylation
Research Areas
- Lipid and Metabolism
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/B4GALT1
bosterbio.com/bosterbio-gene-info-cards/B4GALT1
References
PMID: 3144273 by Masri K.A., et al. Identification of the full-length coding sequence for human galactosyltransferase (beta-N-acetylglucosaminide: beta 1,4- galactosyltransferase).
PMID: 2124683 by Watzele G., et al. Near identity of HeLa cell galactosyltransferase with the human placental enzyme.