BCAT1 Antibodies

AND BCAT1 ELISA kits, BCAT1 Proteins

Many biological assays use antibodies to detect BCAT1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with BCAT1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop BCAT1 antibodies...

We validate the specificity of these antibodies to BCAT1 by testing them on tissues known to express BCAT1 positively and negatively. Browse below to find the BCAT1 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for BCAT1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the BCAT1 Western Blot Guide

BCAT1 Infographic by Boster Bio

All BCAT1 Products

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Product

Figures

Specificity

Applications

Price

Anti-BCAT1 Antibody Picoband®

1 Citations

Hypoxia resultes in the increased expression of BCAT1

Upregulation of BCAT1 expression induced by hypoxia leads to PASMC autophagy

BCAT1 regulates autophagy through the endoplasmic reticulum stress pathway

Human, Mouse, Rat

Flow Cytometry, IHC, WB

$370
Cat # PA1538
100 μg/vial

Anti-BCAT1 Antibody Picoband®

Western blot analysis of BCAT1 using anti-BCAT1 antibody (A05089-2)

IHC analysis of BCAT1 using anti-BCAT1 antibody (A05089-2)

Human, Mouse, Rat

ELISA, Flow Cytometry, IHC, WB

$370
Cat # A05089-2
100 μg/vial

BCAT1 (NM_001178091) Human Over-expression Lysate

BCAT1 Human Over-expression Lysates NM_001178091

Human

$628
Cat # LS000586
20 µg, 100 µg

Human BCAT1 Recombinant Protein

SDS-PAGE

$250
Cat # PROTP54687
Starting from 20ug

BCAT1 Overview

Facts about Branched-chain-amino-acid aminotransferase, cytosolic.

BCAT1 3D structure. Source: alphafold

Branched-chain-amino-acid aminotransferase, cytosolic (BCAT1)

Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine. .

Gene Information

Human
Gene Name:	BCAT1
Uniprot:	P54687
Entrez:	586

Family

Belongs to:

class-IV pyridoxal-phosphate-dependent aminotransferase family

Alternative Names

BCAT(c); BCAT1; BCAT-1; BCATC; BCT1; BCT1PNAS121; branched chain amino-acid transaminase 1, cytosolic; branched chain aminotransferase 1, cytosolic; branched-chain-amino-acid aminotransferase, cytosolic; DKFZp686E12175; EC 2.6.1.42; ECA39; MECA39; placental protein 18; PNAS121; PP18; Protein ECA39

Molecular Weight

Mass (kDA):
42.966 kDA

Genomic Context


Human

Location:	12p12.1
Sequence:	12; NC_000012.12 (24810024..24949101, complement)

Tissue Specificity

During embryogenesis, expressed in the brain and kidney. Overexpressed in MYC-induced tumors such as Burkitt's lymphoma.

Subcellular Localizations

Cytoplasm.

Diseases

Neoplasms
Malignant Neoplasms
Cell Transformation, Neoplastic
Tissue Adhesions
Neoplasm Metastasis
Burkitt Lymphoma
Carcinoma
Lymphoma
Ovarian Neoplasm
Diabetes Mellitus
Nervousness
Adenoma
Malnutrition

Malignant Neoplasm Of Breast
Hepatitis C, Chronic
Seminoma
Childhood Ependymoma
Ulcer
Neoplasms, Glandular And Epithelial
Varicose Ulcer

Pathways

Cell Adhesion
Cell Proliferation
Cell Cycle
Oncogenesis
Transport
Fruit Development
Localization
Endocrine Signaling
Coagulation
Fatty Acid Transport
Cell Death

T Cell Proliferation
Regulation Of Cell Proliferation
Cell Growth
Wound Healing
Pathogenesis
Rna Interference

PTMs

Phosphorylation

Amination

Research Areas

Cell Cycle and Replication
Core ESC-Like Genes
Stem Cell Markers

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/BCAT1

References

PMID: 8692959 by Schuldiner O., et al. ECA39, a conserved gene regulated by c-Myc in mice, is involved in G1/S cell cycle regulation in yeast.

PMID: 16141215 by Goto M., et al. Structural determinants for branched-chain aminotransferase isozyme- specific inhibition by the anticonvulsant drug gabapentin.