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Bestrophin-3 Antibodies

AND BEST3 ELISA kits, Bestrophin-3 Proteins

Many biological assays use antibodies to detect Bestrophin-3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Bestrophin-3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Bestrophin-3 antibodies...

We validate the specificity of these antibodies to Bestrophin-3 by testing them on tissues known to express BEST3 positively and negatively. Browse below to find the BEST3 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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BEST3 Infographic by Boster Bio

BEST3 protein infographic

All BEST3 Products

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Specificity

Applications

Price

Bestrophin 3 (BEST3) (NM_152439) Human Recombinant Protein

Coomassie blue staining of purified BEST3 protein

Coomassie blue staining of purified BEST3 protein

$1062
Cat # PROTQ8N1M1
20 µg

Anti-Bestrophin 3 (BEST3) Mouse Monoclonal Antibody [Clone ID: OTI2H3]

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY BEST3 (Right lane) cDNA for 48 hrs and lysed

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY BEST3 (Right lane) cDNA for 48 hrs and lysed

HEK293T cells transfected with either BEST3 (Myc-DDK-tagged) overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-BEST3 antibody (M11218)

Flow cytometric Analysis of Hela cells

Human, Mouse, Rat

Flow Cytometry, IF, WB

$523
Cat # M11218
100 µl

Bestrophin 3 (BEST3) (NM_152439) Human Over-expression Lysate

Bestrophin 3 (BEST3) Human Over-expression Lysates NM_032735

Bestrophin 3 (BEST3) Human Over-expression Lysates NM_032735

Bestrophin 3 (BEST3) Human Over-expression Lysates NM_152439

Human

$960
Cat # LS144453
20 µg, 100 µg

BEST3 Overview

Facts about Bestrophin-3.

BEST3 3D structure

BEST3 3D structure. Source: alphafold

Bestrophin-3 (BEST3)

Forms calcium-sensitive chloride channels. Permeable to bicarbonate.

.

Gene Information

Human
Gene Name:	BEST3
Uniprot:	Q8N1M1
Entrez:	144453

Gene Information

Family

Belongs to:

bestrophin family

Family

Alternative Names

bestrophin 3; bestrophin-3; MGC13168; MGC40411; vitelliform macular dystrophy 2-like 3; VMD2L3Vitelliform macular dystrophy 2-like protein 3

Molecular Weight

Mass (kDA):
76.107 kDA

Molecular Weight

Genomic Context


Human

Location:	12q15
Sequence:	12; NC_000012.12 (69643508..69699416, complement)

Tissue Specificity

Present in skeletal muscle and weakly in brain, spinal cord, bone marrow and retina.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

Subcellular Localization

Diseases

Cystic Fibrosis
Fibrocystic Disease Of Pancreas
Age Related Macular Degeneration
Fibrosis
Edema
Encephalitis
Inflammation

Retinal Diseases
Vitelliform Macular Dystrophy

Disease

Pathways

Secretion
Transport
Phagocytosis
Anion Homeostasis
Ion Transport
Localization

Pathways

Bosterbio | ELISA Kits, Antibodies, Antibody Company

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/BEST3

References

PMID: 12032738 by Stoehr H., et al. Three novel human VMD2-like genes are members of the evolutionary highly conserved RFP-TM family.

PMID: 12907679 by Tsunenari T., et al. Structure-function analysis of the bestrophin family of anion channels.