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- Table of Contents
BNIP3L Antibodies
AND BNIP3L ELISA kits, BNIP3L Proteins
Many biological assays use antibodies to detect BNIP3L, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with BNIP3L in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop BNIP3L antibodies...
Designing a Western blot for BNIP3L? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the BNIP3L Western Blot GuideDesigning an IHC experiment for BNIP3L? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the BNIP3L IHC GuideBNIP3L Infographic by Boster Bio
All BNIP3L Products
Product
Figures
Specificity
Applications
Price
Anti-BNIP3L/Nix Rabbit Monoclonal Antibody
4 Citations
Human, Mouse, Rat
IHC, WB
$370
Cat # M03107
100 μl
Cat # M03107
100 μl
Human, Mouse, Rat
Flow Cytometry, IF, ICC, WB
$370
Cat # A03107-3
100 μg/vial
Cat # A03107-3
100 μg/vial
BNIP3L Overview
Facts about BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like.
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like (BNIP3L)
Induces apoptosis. Interacts with viral and cellular anti-apoptosis proteins.
Can conquer the suppressors BCL-2 and BCL-XL, although elevated levels of BCL-XL expression will inhibit apoptosis. Inhibits apoptosis induced by BNIP3.
Gene Information
| Human | |
|---|---|
| Gene Name: | BNIP3L |
| Uniprot: | O60238 |
| Entrez: | 665 |
Family
| Belongs to: |
|---|
| NIP3 family |
Alternative Names
Adenovirus E1B19K-binding protein B5; BCL2/adenovirus E1B 19 kDa protein-interacting protein 3A; BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like; BCL2/adenovirus E1B 19-kd protein-interacting protein 3a; BCL2/adenovirus E1B 19kDa interacting protein 3-like; BNIP3a; BNIP3H; BNIP3L; Nip3L; NIP3-like protein X; Nix; NIXBCL2/adenovirus E1B 19kD-interacting protein 3-like
Molecular Weight
Mass (kDA):
23.93 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 8p21.2 |
| Sequence: | 8; NC_000008.11 (26383054..26413127) |
Subcellular Localizations
Nucleus envelope. Endoplasmic reticulum. Mitochondrion outer membrane. Membrane; Single-pass membrane protein. Colocalizes with SPATA18 at the mitochondrion outer membrane.
Diseases
- Neoplasms
- Malignant Neoplasms
- Hypoxia
- Mammary Neoplasms
- Carcinoma
- Anoxia
- Malignant Neoplasm Of Breast
- Heart Failure
- Malignant Paraganglionic Neoplasm
- Neoplasm Metastasis
- Cell Transformation, Neoplastic
- Cardiomyopathies
Interacting Proteins
- ADIPOQ
- ATP13A2
- BAD
- BCL2
- BNIP3
- CLEC7A
- FATE1
- LDLRAD1
- SMCO4
- TMEM11
Pathways
- Cell Death
- Autophagy
- Cell Cycle
- Response To Hypoxia
- Localization
- Transport
- Programmed Cell Death
- Angiogenesis
- Cell Proliferation
- Autophagic Cell Death
- Induction Of Apoptosis
- Methylation
- Glycolysis
PTMs
- Methylation
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/BNIP3L
bosterbio.com/bosterbio-gene-info-cards/BNIP3L
References
PMID: 9523198 by Matsushima M., et al. Isolation, mapping, and functional analysis of a novel human cDNA (BNIP3L) encoding a protein homologous to human NIP3.
PMID: 9867803 by Chen G., et al. Nix and Nip3 form a subfamily of pro-apoptotic mitochondrial proteins.
1 Publications of Boster BNIP3L Antibodies & ELISA Kits
- PubMed ID: 10.1080/15548627.2020.1728096, Mutant HTT (huntingtin) impairs mitophagy in a cellular model of Huntington dise...
*More publications can be found for each product on its corresponding product page