Probetacellulin Antibodies

Probetacellulin (BTC)

Growth factor that binds to EGFR, ERBB4 and other EGF receptor family members. Potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells.

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Gene Information

Human
Gene Name:	BTC
Uniprot:	P35070
Entrez:	685

Family

Belongs to:
No superfamily

Alternative Names

Betacellulin; BTC; probetacellulin

Molecular Weight

Mass (kDA):
19.746 kDA

Genomic Context

Human
Location:	4q13.3
Sequence:	4; NC_000004.12 (74744759..74794718, complement)

Subcellular Localizations

[Betacellulin]: Secreted, extracellular space.; [Probetacellulin]: Cell membrane; Single-pass type I membrane protein.

Diseases

• Malignant Neoplasms
• Neoplasms
• Carcinoma
• Biliary Tract Cancer
• Biliary Tract Neoplasm
• Diabetes Mellitus
• Cholangiocarcinoma
• Adenocarcinoma
• Malignant Neoplasm Of Gallbladder
• Carcinogenesis
• Multiple Organ Failure
• Gallbladder Neoplasm
• Diabetes Mellitus, Experimental

• Malignant Squamous Cell Neoplasm
• Malignant Neoplasm Of Breast
• Mammary Neoplasms
• Malignant Paraganglionic Neoplasm
• Bile Duct Neoplasms
• Anemia
• Diabetes Mellitus, Insulin-dependent

Interacting Proteins

• GMPPA
• KRT31
• S100A4
• SGTA

Pathways

• Transport
• Cell Proliferation
• Regeneration
• Secretion
• Cell Cycle
• Insulin Secretion
• Oocyte Maturation
• Pathogenesis
• Localization
• Cell Growth
• Methylation
• Ovulation
• Angiogenesis

• Fertilization
• Embryo Development
• Cell Differentiation
• Cytolysis
• Dna Methylation
• S Phase
• Cell Cycle Arrest

PTMs

• Phosphorylation
• Cleavage
• Nitration
• Methylation
• Oxidation
• Hydroxylation
• Glycosylation
• Amination

• Demethylation
• Dephosphorylation
• Acylation
• Bromination
• Ubiquitination
• Iodination
• Biotinylation
• Acetylation

• Palmitoylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/BTC

Boster Bio - Best Uses Of The BTC Marker

If you're interested in becoming a biomedical researcher, you'll want to learn more about Boster Bio and its anti-BTC antibody Picoband(tm). If you're already an expert in a specific field, you can also use the marker to get product credits for your results. Boster scientists are all over the world, so you can use this tool to gain access to the latest and greatest research and results.

Boster Bio Anti-Btc Antibody Picoband(tm)

Boster Bio Anti-BTC Antibody is a humanized monoclonal antibody which is validated and tested in ELISA, Flow Cytometry, and Immunofluorescence. It reacts with human, mouse, and rat cells. All Boster Bio antibodies are validated before they are released for sale. Scientists may request product credits from Boster Bio for the validation of their research.