Bcl-2-like protein 10 Antibodies

AND BCL2L10 ELISA kits, Bcl-2-like protein 10 Proteins

Many biological assays use antibodies to detect Bcl-2-like protein 10, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Bcl-2-like protein 10 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Bcl-2-like protein 10 antibodies...

We validate the specificity of these antibodies to Bcl-2-like protein 10 by testing them on tissues known to express BCL2L10 positively and negatively. Browse below to find the BCL2L10 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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BCL2L10 Infographic by Boster Bio

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Anti-Bcl-B BCL2L10 Antibody

Western blot analysis of Bcl-B in Jurkat cell lysate with Bcl-B antibody at (A) 1 and (B) 2 μg/mL

Immunocytochemistry of Bcl-B in Jurkat cells with Bcl-B antibody at 10 μg/mL

Human

ELISA, ICC, WB

$481
Cat # A07380
0.1 mg

Human BCL2L10 Recombinant Protein

SDS-PAGE

$250
Cat # PROTQ9HD36
Starting from 20ug

BCL2L10 Overview

Facts about Bcl-2-like protein 10.

BCL2L10 3D structure. Source: alphafold

Bcl-2-like protein 10 (BCL2L10)

Promotes cell survival. Suppresses apoptosis induced by BAX but not BAK.

Gene Information

Human
Gene Name:	BCL2L10
Uniprot:	Q9HD36
Entrez:	10017

Family

Belongs to:

Bcl-2 family

Alternative Names

Apoptosis regulator Bcl-B; apoptotic protein NrH; bcl2-L-10; BCL2-like 10 (apoptosis facilitator); bcl-2-like protein 10; BCLB; BCL-B; Boo; Diva; MGC129810; MGC129811

Molecular Weight

Mass (kDA):
23.204 kDA

Genomic Context


Human

Location:	15q21.2
Sequence:	15; NC_000015.10 (52109263..52112775, complement)

Tissue Specificity

Widely expressed in adult tissues. Preferentially expressed in lung, liver and kidney.

Subcellular Localizations

Mitochondrion. Nucleus membrane.

Diseases

Malignant Neoplasms
Neoplasms
Stomach Neoplasms
Malignant Neoplasm Of Stomach
Leukemia
Carcinogenesis
Carcinoma
Leukemia, Myelocytic, Acute
Myeloid Leukemia
Dysmyelopoietic Syndromes
Adenocarcinoma
Immunologic Deficiency Syndromes

Mammary Neoplasms
Lymphoma
Cell Transformation, Neoplastic
Neoplasm Metastasis
Non-neoplastic Disorder
Metastatic Malignant Neoplasm To The Lymph Node
Tumor Progression

Interacting Proteins

BAX
BCL2L11
BIK

Pathways

Methylation
Dna Methylation
Oocyte Maturation
Cell Death
Cell Proliferation
Commitment To Apoptosis
Dna Hypomethylation
Fertilization
Metaphase
Localization

Demethylation
Drug Resistance
Cell Cycle
Pathogenesis
Rna Interference

PTMs

Methylation
Demethylation

Phosphorylation
Cleavage

Ubiquitination

Research Areas

Apoptosis

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/BCL2L10

References

PMID: 11689480 by Zhang H., et al. Bcl2-L-10, a novel anti-apoptotic member of the Bcl-2 family, blocks apoptosis in the mitochondria death pathway but not in the death receptor pathway.

PMID: 11278245 by Ke N., et al. Bcl-B, a novel Bcl-2 family member that differentially binds and regulates Bax and Bak.