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- Table of Contents
Osteocalcin Antibodies
AND BGLAP ELISA kits, Osteocalcin Proteins
Many biological assays use antibodies to detect Osteocalcin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Osteocalcin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Osteocalcin antibodies...
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BGLAP Infographic by Boster Bio
All BGLAP Products
Product
Figures
Specificity
Applications
Price
Anti-Osteocalcin/BGLAP Antibody
19 Citations 13 Q&As
Rat
Flow Cytometry, IHC
$370
Cat # PB9920
100 μg/vial
Cat # PB9920
100 μg/vial
BGLAP Overview
Facts about Osteocalcin.
Osteocalcin (BGLAP)
Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | BGLAP |
| Uniprot: | P02818 |
| Entrez: | 632 |
Family
| Belongs to: |
|---|
| osteocalcin/matrix Gla protein family |
Alternative Names
BGLAP; BGP; bone gamma-carboxyglutamate (gla) protein (osteocalcin); bone gamma-carboxyglutamate (gla) protein; Bone Gla protein; Gamma-carboxyglutamic acid-containing protein; OC; OCN; Osteocalcin
Molecular Weight
Mass (kDA):
10.963 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1q22 |
| Sequence: | 1; NC_000001.11 (156242184..156243317) |
Subcellular Localizations
Secreted.
Diseases
- Fracture
- Osteoporosis
- Diabetes Mellitus
- Malignant Neoplasms
- Headache
- Diabetes Mellitus, Non-insulin-dependent
- Growth Arrest
- Insulin Resistance
- Osteopenia
- Acute Lymphocytic Leukemia
- Insulin Sensitivity
- Leukemia
Pathways
- Osteoblast Differentiation
- Bone Resorption
- Cell Proliferation
- Regeneration
- Bone Development
- Ossification
- Chondrocyte Differentiation
- Cell Differentiation
- Senescence
- Methylation
- Secretion
- Transport
- Osteoclast Differentiation
PTMs
- Methylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/BGLAP
bosterbio.com/bosterbio-gene-info-cards/BGLAP
References
PMID: 2336375 by Kiefer M.C., et al. The cDNA and derived amino acid sequences of human and bovine bone Gla protein.
PMID: 3019668 by Celeste A.J., et al. Isolation of the human gene for bone gla protein utilizing mouse and rat cDNA clones.
12 Publications of Boster Osteocalcin Antibodies & ELISA Kits
- PubMed ID: 10.1371/journal.pone.0181133, Role of glucocorticoid-induced leucine zipper (GILZ) in inflammatory bone loss
- PubMed ID: -, Caiyun Mu,Ye He,Yan Hu,Menghuan Li,Maowen Chen,Rong Wang,Yang Xiang, Zhong Luo,K...
- PubMed ID: -, Vadim Veiko,Yulia Karlagina,Tatiana Itina,Daria Kuznetsova,Vadim Elagin,Elena Za...
- PubMed ID: 33274496, Tian Y,Shao Q,Tang Y,Li X,Qi X,Jiang R,Liang Y,Kang F.HIF-1α Regulates Osteocla...
- PubMed ID: 26648442, Intramuscular injection of bone marrow mononuclear cells contributes to bone rep...
- PubMed ID: 24265840, The Osteogenic Potential of Mesoporous Bioglasses/Silk and Non-Mesoporous Biogla...
- PubMed ID: 28791357, Synergistic effects of fibroblast growth factor-2 and bone morphogenetic protein...
- PubMed ID: 28771604, Role of glucocorticoid-induced leucine zipper (GILZ) in inflammatory bone loss
- PubMed ID: 26078764, Effects of Naringin on Proliferation and Osteogenic Differentiation of Human Per...
- PubMed ID: 23990941, Electrospun Poly(L-lactide)/Poly(?-caprolactone) Blend Nanofibrous Scaffold: Cha...
- PubMed ID: 28253279, Liu Q, Ma Y, Wang J, Zhu X, Yang Y, Mei Y. PLoS One. 2017 Mar 2;12(3):e0172693. ...
- PubMed ID: 25109926, Xu F, Dong Y, Huang X, Li M, Qin L, Ren Y, Guo F, Chen A, Huang S. Mol Med Rep. ...
*More publications can be found for each product on its corresponding product page