C10orf90 Antibodies

AND C10orf90 ELISA kits, C10orf90 Proteins

Many biological assays use antibodies to detect C10orf90, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with C10orf90 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop C10orf90 antibodies...

We validate the specificity of these antibodies to C10orf90 by testing them on tissues known to express C10orf90 positively and negatively. Browse below to find the C10orf90 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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C10orf90 Infographic by Boster Bio

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C10orf90 Overview

Facts about (E2-independent) E3 ubiquitin-conjugating enzyme FATS.

C10orf90 3D structure. Source: alphafold

(E2-independent) E3 ubiquitin-conjugating enzyme FATS (C10orf90)

Tumor suppressor that is required to sustain G2/M checkpoint after DNA damage. Mediates CDKN1A/p21 protein stability in a ubiquitin-independent way (By similarity).

May have a function in the assembly of primary cilia. .

Gene Information

Human
Gene Name:	C10orf90
Uniprot:	Q96M02
Entrez:	118611

Family

Belongs to:

No superfamily

Alternative Names

bA422P15.2; chromosome 10 open reading frame 90; FATS; fragile-site associated tumor suppressor; RP11-422P15.2

Molecular Weight

Mass (kDA):
77.91 kDA

Genomic Context


Human

Location:	10q26.2
Sequence:	10; NC_000010.11 (126424997..126670510, complement)

Subcellular Localizations

Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Localizes to the actin cytoskeleton in a proportion of cells. Colocalizes with centriolar acetylated tubulin.

Diseases

Small Cell Carcinoma Of Lung
Malignant Neoplasms
Lung Neoplasms
Non-small Cell Lung Carcinoma
Neoplasms
Alstrom Syndrome
Malignant Neoplasm Of Lung

Carcinogenesis

Pathways

Cilium Assembly
Reverse Transcription

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/C10orf90

References

PMID: 20844083 by Knorz V.J., et al. Centriolar association of ALMS1 and likely centrosomal functions of the ALMS motif-containing proteins C10orf90 and KIAA1731.