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- Table of Contents
Carbonic anhydrase 4 Antibodies
AND CA4 ELISA kits, Carbonic anhydrase 4 Proteins
Many biological assays use antibodies to detect Carbonic anhydrase 4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Carbonic anhydrase 4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Carbonic anhydrase 4 antibodies...
Designing a Western blot for Carbonic anhydrase 4? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the CA4 Western Blot GuideCA4 Infographic by Boster Bio
All CA4 Products
Product
Figures
Specificity
Applications
Price
Human
ELISA
$500
Cat # EZ1939
5 plates/kit
Cat # EZ1939
5 plates/kit
Human
ELISA
$750
Cat # EK1939
96 wells/kit, with removable strips.
Cat # EK1939
96 wells/kit, with removable strips.
Mouse
ELISA
$750
Cat # EK1940
96 wells/kit, with removable strips.
Cat # EK1940
96 wells/kit, with removable strips.
Mouse, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A01523-3
100 μg/vial
Cat # A01523-3
100 μg/vial
Human, Mouse, Rat
WB
$370
Cat # A01523-1
100 μg/vial
Cat # A01523-1
100 μg/vial
Human
$628
Cat # LS000762
20 µg, 100 µg
Cat # LS000762
20 µg, 100 µg
CA4 Overview
Facts about Carbonic anhydrase 4.
Carbonic anhydrase 4 (CA4)
Reversible hydration of carbon dioxide. May stimulate the sodium/bicarbonate transporter activity of SLC4A4 that acts in pH homeostasis.
It is essential for acid overload elimination from the retina and retina epithelium, and acid release from the choriocapillaris in the choroid. .
Gene Information
| Human | |
|---|---|
| Gene Name: | CA4 |
| Uniprot: | P22748 |
| Entrez: | 762 |
Family
| Belongs to: |
|---|
| alpha-carbonic anhydrase family |
Alternative Names
CA4; CAIV; CA-IV; Car4; Carbonate dehydratase IV; carbonic anhydrase 4; Carbonic Anhydrase IV; carbonic anhydrase IVRP17; carbonic dehydratase IV; EC 4.2.1.1; retinitis pigmentosa 17 (autosomal dominant); RP17
Molecular Weight
Mass (kDA):
35.032 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 17q23.1 |
| Sequence: | 17; NC_000017.11 (60149942..60179021) |
Tissue Specificity
Expressed in the endothelium of the choriocapillaris in eyes (at protein level). Not expressed in the retinal epithelium at detectable levels.
Subcellular Localizations
Cell membrane; Lipid-anchor, GPI-anchor.
Diseases
- Ischemia
- Epilepsy
- Alzheimer's Disease
- Nerve Degeneration
- Brain Ischemia
- Epilepsy, Temporal Lobe
- Sclerosis
- Brain Injuries
- Transient Ischemic Attack
- Nervousness
- Cerebral Ischemia
- Schizophrenia
Pathways
- Localization
- Cell Death
- Aging
- Pathogenesis
- Innervation
- Neuroprotection
- Brain Development
- Transport
- Lactation
- Neurogenesis
- Cell Adhesion
- Cell Cycle
- Translation
PTMs
- Phosphorylation
- Oxidation
- Dephosphorylation
- Cleavage
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CA4
bosterbio.com/bosterbio-gene-info-cards/CA4
References
PMID: 1311094 by Okuyama T., et al. Human carbonic anhydrase IV: cDNA cloning, sequence comparison, and expression in COS cell membranes.
PMID: 8325641 by Okuyama T., et al. Genomic organization and localization of gene for human carbonic anhydrase IV to chromosome 17q.