Cell adhesion molecule 3 Antibodies

AND CADM3 ELISA kits, Cell adhesion molecule 3 Proteins

Many biological assays use antibodies to detect Cell adhesion molecule 3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Cell adhesion molecule 3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Cell adhesion molecule 3 antibodies...

We validate the specificity of these antibodies to Cell adhesion molecule 3 by testing them on tissues known to express CADM3 positively and negatively. Browse below to find the CADM3 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CADM3 Infographic by Boster Bio

All CADM3 Products

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Anti-Cell adhesion molecule 3 CADM3 Antibody

Western blot analysis of CADM3 in human brain tissue lysate with CADM3 antibody at (A) 1 and (B) 2 μg/ml

Immunohistochemistry of CADM3 in mouse brain tissue with CADM3 antibody at 5 μg/ml

Immunofluorescence of CADM3 in mouse brain tissue with CADM3 antibody at 20 μg/ml

Human, Mouse, Rat

ELISA, IF, IHC-P, WB

$481
Cat # A08747
0.1 mg

CADM3 (NM_021189) Human Recombinant Protein

Coomassie blue staining of purified CADM3 protein

$1249
Cat # PROTQ8N126
20 µg

CADM3 (NM_021189) Human Over-expression Lysate

Human

$960
Cat # LS057863
20 µg, 100 µg

CADM3 Overview

Facts about Cell adhesion molecule 3.

CADM3 3D structure. Source: alphafold

Cell adhesion molecule 3 (CADM3)

Involved from the cell-cell adhesion. Has both calcium- independent homophilic cell-cell adhesion activity and calcium- independent heterophilic cell-cell adhesion activity with IGSF4, NECTIN1 and NECTIN3.

Interaction with EPB41L1 may regulate structure or function of cell-cell junctions (By similarity). .

Gene Information

Human
Gene Name:	CADM3
Uniprot:	Q8N126
Entrez:	57863

Family

Belongs to:

nectin family

Alternative Names

BIgR; Brain immunoglobulin receptor; CADM3; cell adhesion molecule 3; IGSF4B; IGSF4BSynCAM3; Immunoglobulin superfamily member 4B; member 4B; Necl-1; NECL1TSLC1-like protein 1; Nectin-like protein 1; Synaptic cell adhesion molecule 3; SynCAM3; TSLC1-like 1; TSLL1; TSLL1SYNCAM3

Molecular Weight

Mass (kDA):
43.3 kDA

Genomic Context


Human

Location:	1q23.2
Sequence:	1; NC_000001.11 (159171592..159203313)

Tissue Specificity

Isoform 1 is expressed mainly in adult and fetal brain. Isoform 2 is highly expressed in adult brain and weakly expressed in placenta. In brain, Isoform 2 is highly expressed in cerebellum.

Subcellular Localizations

Cell membrane; Single-pass type I membrane protein. Cell junction.

Diseases

Tissue Adhesions
Glioma
Neoplasms
Malignant Neoplasm Of Prostate
Lung Neoplasms
Non-small Cell Lung Carcinoma
Brain Neoplasms
Malignant Neoplasm Of Lung
Malignant Neoplasms

Corneal Diseases
Nervousness
Traditional Serrated Adenoma
Inflammation

Pathways

Cell-cell Adhesion
Heterophilic Cell-cell Adhesion
Cell Adhesion
Methylation
Histone Deacetylation
Cell Proliferation
System Development
Cell Cycle
Nervous System Development

Glycosylation
Localization
Cell Cycle Arrest

PTMs

Glycosylation

Deacetylation

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CADM3

References

PMID: 11536053 by Fukuhara H., et al. Isolation of the TSLL1 and TSLL2 genes, members of the tumor suppressor TSLC1 gene family encoding transmembrane proteins.

PMID: 15893517 by Zhou Y., et al. Nectin-like molecule 1 is a protein 4.1N associated protein and recruits protein 4.1N from cytoplasm to the plasma membrane.