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- Table of Contents
Facts about Caspase recruitment domain-containing protein 9.
monocytogenes. Likely controls various innate immune response pathways depending on the intracellular pathogen.
| Human | |
|---|---|
| Gene Name: | CARD9 |
| Uniprot: | Q9H257 |
| Entrez: | 64170 |

| Belongs to: |
|---|
| No superfamily |

CANDF2; CARD9; caspase recruitment domain family, member 9; caspase recruitment domain-containing protein 9; hCARD9
Mass (kDA):
62.241 kDA

| Human | |
|---|---|
| Location: | 9q34.3 |
| Sequence: | 9; NC_000009.12 (136363956..136373669, complement) |
Highly expressed in spleen. Also detected in liver, placenta, lung, peripheral blood leukocytes and in brain.
Cytoplasm.




PMID: 11053425 by Bertin J., et al. CARD9 is a novel caspase recruitment domain-containing protein that interacts with Bcl10/CLAP and activates NF-kappa B.
PMID: 19864672 by Glocker E.-O., et al. A homozygous CARD9 mutation in a family with susceptibility to fungal infections.