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- Table of Contents
CARD9 Antibodies
AND CARD9 ELISA kits, CARD9 Proteins
Many biological assays use antibodies to detect CARD9, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CARD9 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CARD9 antibodies...
Designing a Western blot for CARD9? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the CARD9 Western Blot GuideDesigning an IHC experiment for CARD9? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the CARD9 IHC GuideCARD9 Infographic by Boster Bio
All CARD9 Products
Product
Figures
Specificity
Applications
Price
Human
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A01410-1
100 μg/vial
Cat # A01410-1
100 μg/vial
Human
ELISA, Flow Cytometry, IF, ICC, WB
$370
Cat # A01412-2
100 µg/vial
Cat # A01412-2
100 µg/vial
CARD9 Overview
Facts about Caspase recruitment domain-containing protein 9.
Caspase recruitment domain-containing protein 9 (CARD9)
Adapter protein that plays a key role in innate immune response to a number of intracellular pathogens, such as C.albicans and L.
monocytogenes. Likely controls various innate immune response pathways depending on the intracellular pathogen.
Gene Information
| Human | |
|---|---|
| Gene Name: | CARD9 |
| Uniprot: | Q9H257 |
| Entrez: | 64170 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
CANDF2; CARD9; caspase recruitment domain family, member 9; caspase recruitment domain-containing protein 9; hCARD9
Molecular Weight
Mass (kDA):
62.241 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 9q34.3 |
| Sequence: | 9; NC_000009.12 (136363956..136373669, complement) |
Tissue Specificity
Highly expressed in spleen. Also detected in liver, placenta, lung, peripheral blood leukocytes and in brain.
Subcellular Localizations
Cytoplasm.
Diseases
- Mycoses
- Infective Disorder
- Candidiasis
- Inflammation
- Candidiasis, Chronic Mucocutaneous
- Crohn Disease
- Immunologic Deficiency Syndromes
- Innate Immune Response
- Autoimmune Reaction
- Intestinal Diseases
- Inflammatory Bowel Diseases
- Ulcer
Pathways
- Cytokine Production
- Pathogenesis
- Immune Response
- Phagocytosis
- Innate Immune Response
- Secretion
- Cell Activation
- Cell Death
- Autophagy
- Proteolysis
- Cell Cycle
- Cell Differentiation
- Interphase
PTMs
- Phosphorylation
- Cleavage
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CARD9
bosterbio.com/bosterbio-gene-info-cards/CARD9
References
PMID: 11053425 by Bertin J., et al. CARD9 is a novel caspase recruitment domain-containing protein that interacts with Bcl10/CLAP and activates NF-kappa B.
PMID: 19864672 by Glocker E.-O., et al. A homozygous CARD9 mutation in a family with susceptibility to fungal infections.