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Caveolin-2 Antibodies
AND CAV2 ELISA kits, Caveolin-2 Proteins
Many biological assays use antibodies to detect Caveolin-2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Caveolin-2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Caveolin-2 antibodies...
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CAV2 Infographic by Boster Bio
All CAV2 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # PB9166
100 μg/vial
Cat # PB9166
100 μg/vial
Human, Monkey, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A01574
100 μg/vial
Cat # A01574
100 μg/vial
CAV2 Overview
Facts about Caveolin-2.
Caveolin-2 (CAV2)
May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.
Acts as an accessory protein together with CAV1 in targeting to lipid rafts and driving caveolae formation. The Ser-36 phosphorylated form has a role in modulating mitosis in endothelial cells.
Gene Information
| Human | |
|---|---|
| Gene Name: | CAV2 |
| Uniprot: | P51636 |
| Entrez: | 858 |
Family
| Belongs to: |
|---|
| caveolin family |
Alternative Names
CAV; CAV2; caveolae protein, 20-kD; caveolin 2 isoform a and b; caveolin 2; Caveolin2; Caveolin-2; MGC12294
Molecular Weight
Mass (kDA):
18.291 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 7q31.2 |
| Sequence: | 7; NC_000007.14 (116499738..116508541) |
Tissue Specificity
Expressed in endothelial cells, smooth muscle cells, skeletal myoblasts and fibroblasts.
Subcellular Localizations
Nucleus. Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein. Membrane, caveola; Peripheral membrane protein. Potential hairpin-like structure in the membrane. Membrane protein of caveolae. Tyr-19-phosphorylated form is enriched at sites of cell-cell contact and is translocated to the nucleus in complex with MAPK1 in response to insulin (By similarity). Tyr-27-phosphorylated form is located both in the cytoplasm and plasma membrane. CAV1-mediated Ser-23-phosphorylated form locates to the plasma membrane. Ser-36-phosphorylated form reside
Diseases
- Malignant Neoplasms
- Neoplasms
- Carcinoma
- Adenovirus Infections
- Glaucoma, Open-angle
- Glaucoma
- Bronchiolitis
- Primary Open Angle Glaucoma
- Lung Neoplasms
- Bronchiolitis, Viral
- Malignant Neoplasm Of Lung
- Infective Disorder
- Malignant Neoplasm Of Breast
Interacting Proteins
- CAV1
Pathways
- Pathogenesis
- Localization
- Transport
- Tropism
- Membrane Depolarization
- Cell Cycle
- Synaptic Transmission
- Endocytosis
- Lung Growth
- Methylation
- Cell Death
- Cholesterol Homeostasis
- Golgi Localization
PTMs
- Phosphorylation
- Reduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CAV2
bosterbio.com/bosterbio-gene-info-cards/CAV2
References
PMID: 8552590 by Scherer P.E., et al. Identification, sequence, and expression of caveolin-2 defines a caveolin gene family.
PMID: 9361015 by Scherer P.E., et al. Cell-type and tissue-specific expression of caveolin-2. Caveolins 1 and 2 co-localize and form a stable hetero-oligomeric complex in vivo.
1 Publications of Boster Caveolin-2 Antibodies & ELISA Kits
- PubMed ID: 24175763, Wang Nn, Zhao Lj, Wu Ln, He Mf, Qu Jw, Zhao Yb, Zhao Wz, Li Js, Wang Jh. Asian P...
*More publications can be found for each product on its corresponding product page