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- Table of Contents
Caveolin-2 Antibodies
AND CAV2 ELISA kits, Caveolin-2 Proteins
Many biological assays use antibodies to detect Caveolin-2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Caveolin-2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Caveolin-2 antibodies...
Designing a Western blot for Caveolin-2? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the CAV2 Western Blot GuideCAV2 Infographic by Boster Bio
All CAV2 Products
Product
Figures
Specificity
Applications
Price
Human, Monkey, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A01574
100 μg/vial
Cat # A01574
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # PB9166
100 μg/vial
Cat # PB9166
100 μg/vial
CAV2 Overview
Facts about Caveolin-2.
Caveolin-2 (CAV2)
May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.
Acts as an accessory protein together with CAV1 in targeting to lipid rafts and driving caveolae formation. The Ser-36 phosphorylated form has a role in modulating mitosis in endothelial cells.
Gene Information
| Human | |
|---|---|
| Gene Name: | CAV2 |
| Uniprot: | P51636 |
| Entrez: | 858 |
Family
| Belongs to: |
|---|
| caveolin family |
Alternative Names
CAV; CAV2; caveolae protein, 20-kD; caveolin 2 isoform a and b; caveolin 2; Caveolin2; Caveolin-2; MGC12294
Molecular Weight
Mass (kDA):
18.291 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 7q31.2 |
| Sequence: | 7; NC_000007.14 (116499738..116508541) |
Tissue Specificity
Expressed in endothelial cells, smooth muscle cells, skeletal myoblasts and fibroblasts.
Subcellular Localizations
Nucleus. Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein. Membrane, caveola; Peripheral membrane protein. Potential hairpin-like structure in the membrane. Membrane protein of caveolae. Tyr-19-phosphorylated form is enriched at sites of cell-cell contact and is translocated to the nucleus in complex with MAPK1 in response to insulin (By similarity). Tyr-27-phosphorylated form is located both in the cytoplasm and plasma membrane. CAV1-mediated Ser-23-phosphorylated form locates to the plasma membrane. Ser-36-phosphorylated form reside
Diseases
- Malignant Neoplasms
- Neoplasms
- Carcinoma
- Adenovirus Infections
- Glaucoma, Open-angle
- Glaucoma
- Bronchiolitis
- Primary Open Angle Glaucoma
- Lung Neoplasms
- Bronchiolitis, Viral
- Malignant Neoplasm Of Lung
- Infective Disorder
- Malignant Neoplasm Of Breast
Interacting Proteins
- CAV1
Pathways
- Pathogenesis
- Localization
- Transport
- Tropism
- Membrane Depolarization
- Cell Cycle
- Synaptic Transmission
- Endocytosis
- Lung Growth
- Methylation
- Cell Death
- Cholesterol Homeostasis
- Golgi Localization
PTMs
- Phosphorylation
- Reduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CAV2
bosterbio.com/bosterbio-gene-info-cards/CAV2
References
PMID: 8552590 by Scherer P.E., et al. Identification, sequence, and expression of caveolin-2 defines a caveolin gene family.
PMID: 9361015 by Scherer P.E., et al. Cell-type and tissue-specific expression of caveolin-2. Caveolins 1 and 2 co-localize and form a stable hetero-oligomeric complex in vivo.
1 Publications of Boster Caveolin-2 Antibodies & ELISA Kits
- PubMed ID: 24175763, Wang Nn, Zhao Lj, Wu Ln, He Mf, Qu Jw, Zhao Yb, Zhao Wz, Li Js, Wang Jh. Asian P...
*More publications can be found for each product on its corresponding product page