Cerebral cavernous malformations 2 protein (CCM2)

Part of the CCM signaling pathway which is a crucial regulator of heart and vessel formation and integrity. May act via the insertion of endothelial cell junctions (By similarity).

May serve as a scaffold protein for MAP2K3-MAP3K3 signaling. Seems to play a significant role in the modulation of MAP3K3- dependent p38 activation induced by hyperosmotic shock (By similarity).