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- Table of Contents
CCR3 Antibodies
AND CCR3 ELISA kits, CCR3 Proteins
Many biological assays use antibodies to detect CCR3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CCR3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CCR3 antibodies...
Designing a Western blot for CCR3? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the CCR3 Western Blot GuideCCR3 Infographic by Boster Bio
All CCR3 Products
Product
Figures
Specificity
Applications
Price
Anti-CCR3 Rabbit Monoclonal Antibody
1 Citations
Human, Mouse, Rat
IF, IHC, ICC, WB
$370
Cat # M01748
100 μl
Cat # M01748
100 μl
CCR3 Overview
Facts about C-C chemokine receptor type 3.
C-C chemokine receptor type 3 (CCR3)
Receptor for a C-C type chemokine.
Binds to eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES and MIP-1 delta.Then transduces a signal by increasing the intracellular calcium ions level. Alternative coreceptor with CD4 for HIV-1 infection.
Gene Information
| Human | |
|---|---|
| Gene Name: | CCR3 |
| Uniprot: | P51677 |
| Entrez: | 1232 |
Family
| Belongs to: |
|---|
| G-protein coupled receptor 1 family |
Alternative Names
b-chemokine receptor; CC chemokine receptor 3; C-C chemokine receptor type 3; C-C CKR-3; CCR3; CCR-3; CD193 antigen; CD193; chemokine (C-C motif) receptor 3; CKR3CC-CKR-3CMKBR3CD193; eosinophil CC chemokine receptor 3; Eosinophil eotaxin receptor; MGC102841
Molecular Weight
Mass (kDA):
41.044 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 3p21.31 |
| Sequence: | 3; NC_000003.12 (46210699..46266706) |
Tissue Specificity
In eosinophils as well as trace amounts in neutrophils and monocytes.
Subcellular Localizations
Cell membrane; Multi-pass membrane protein.
Diseases
- Inflammation
- Cholangiocarcinoma
- Hiv Infections
- Asthma
- Immunologic Deficiency Syndromes
- Eosinophilia
- Acquired Immunodeficiency Syndrome
- Allergy
- Tissue Adhesions
- Nervousness
- Neoplasms
- Autoimmune Reaction
Interacting Proteins
- CCL11
Pathways
- Chemotaxis
- Pathogenesis
- Secretion
- Immune Response
- Cell Migration
- Tropism
- Eosinophil Chemotaxis
- Cytokine Production
- Inflammatory Response
- Eosinophil Migration
- Cell Proliferation
- Leukocyte Migration
- Chemokine Production
PTMs
- Phosphorylation
- Cleavage
- Phosphorothioation
- Glycosylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CCR3
bosterbio.com/bosterbio-gene-info-cards/CCR3
References
PMID: 7622448 by Combadiere C., et al. Cloning and functional expression of a human eosinophil CC chemokine receptor.
PMID: 8642344 by Daugherty B.L., et al. Cloning, expression, and characterization of the human eosinophil eotaxin receptor.