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- Table of Contents
CCT4 Antibodies
AND CCT4 ELISA kits, CCT4 Proteins
Many biological assays use antibodies to detect CCT4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CCT4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CCT4 antibodies...
Designing a Western blot for CCT4? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the CCT4 Western Blot GuideCCT4 Infographic by Boster Bio
All CCT4 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, IHC-F, ICC, WB
$370
Cat # PB9927
100 μg/vial
Cat # PB9927
100 μg/vial
CCT4 Overview
Facts about T-complex protein 1 subunit delta.
T-complex protein 1 subunit delta (CCT4)
Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis (PubMed:25467444). The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance (PubMed:25467444).
As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia (PubMed:20080638). The TRiC complex plays a role in the folding of actin and tubulin (Probable).
Gene Information
| Human | |
|---|---|
| Gene Name: | CCT4 |
| Uniprot: | P50991 |
| Entrez: | 10575 |
Family
| Belongs to: |
|---|
| TCP-1 chaperonin family |
Alternative Names
Cctd; CCT-DELTA; chaperonin containing t-complex polypeptide 1, delta subunit; chaperonin containing TCP1, subunit 4 (delta); MGC126165; SRBMGC126164; Stimulator of TAR RNA-binding; T-complex protein 1 subunit delta; TCP-1-delta
Molecular Weight
Mass (kDA):
57.924 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 2p15 |
| Sequence: | 2; NC_000002.12 (61868085..61888671, complement) |
Subcellular Localizations
Cytoplasm. Melanosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, cilium basal body. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Diseases
- Sensory Neuropathy
- Malignant Neoplasms
- Neoplasms
- Pain
- Hereditary Sensory And Autonomic Neuropathies
- Sensory Neuropathy, Hereditary
- Nerve Degeneration
- Stomach Neoplasms
- Neoplasm Metastasis
- Ataxia
- Neuromuscular Diseases
- Ulcer
Interacting Proteins
- CCT2
- OLR1
- TCP1
Pathways
- Translation
- Ribosome Biogenesis
- Cell Migration
- Cell Motility
- Protein Folding
- Innervation
- Localization
PTMs
- Acetylation
Research Areas
- Cell Cycle and Replication
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CCT4
bosterbio.com/bosterbio-gene-info-cards/CCT4
References
PMID: 8626763 by Wu-Baer F., et al. Identification of a group of cellular cofactors that stimulate the binding of RNA polymerase II and TRP-185 to human immunodeficiency virus 1 TAR RNA.
PMID: 9819444 by Won K.-A., et al. Maturation of human cyclin E requires the function of eukaryotic chaperonin CCT.
1 Publications of Boster CCT4 Antibodies & ELISA Kits
- PubMed ID: , Denatured corona proteins mediate the intracellular bioactivities of nanoparticl...
*More publications can be found for each product on its corresponding product page