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- Table of Contents
1 Citations 9 Q&As
4 Citations 16 Q&As
60 Citations 17 Q&As
1 Citations 9 Q&As
17 Citations
6 Citations
3 Citations
Facts about CD44 antigen.
Adhesion with HA plays an important role in cell migration, tumor growth and development. In cancer cells, may play an significant role in invadopodia formation.
| Human | |
|---|---|
| Gene Name: | CD44 |
| Uniprot: | P16070 |
| Entrez: | 960 |

| Belongs to: |
|---|
| No superfamily |

CD44 antigen; CD44 molecule (Indian blood group); CD44; CD44R; CDw44; cell surface glycoprotein CD44; chondroitin sulfate proteoglycan 8; CSPG8; ECMR-III; epican; Extracellular matrix receptor III; GP90 lymphocyte homing/adhesion receptor; HCAM; HCELL; hematopoietic cell E- and L-selectin ligand; Heparan sulfate proteoglycan; Hermes antigen; homing function and Indian blood group system; HUTCH-I; Hyaluronate receptor; IN; LHR; MC56; MDU2; MDU2CD44 antigen (homing function and Indian blood group system); MDU3; MDU3CDW44; MIC4; MIC4MGC10468; MUTCH-I; Pgp1; PGP-1; PGP-I; Phagocytic glycoprotein 1
Mass (kDA):
81.538 kDA

| Human | |
|---|---|
| Location: | 11p13 |
| Sequence: | 11; NC_000011.10 (35139168..35232402) |
Isoform 10 (epithelial isoform) is expressed by cells of epithelium and highly expressed by carcinomas. Expression is repressed in neuroblastoma cells.
Cell membrane; Single-pass type I membrane protein. Cell projection, microvillus. Colocalizes with actin in membrane protrusions at wounding edges. Co-localizes with RDX, EZR and MSN in microvilli. Localizes to cholesterol-rich membrane-bound lipid raft domains.





PMID: 2466575 by Stamenkovic I., et al. A lymphocyte molecule implicated in lymph node homing is a member of the cartilage link protein family.
PMID: 1840487 by Harn H.-J., et al. The multispecific cell adhesion molecule CD44 is represented in reticulocyte cDNA.
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