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Ligand of the T-lymphocyte CD2 glycoprotein.This interaction is important in mediating thymocyte interactions with thymic epithelial cells, antigen-independent and -dependent interactions of T-lymphocytes with target cells and antigen- presenting cells and the T-lymphocyte rosetting with erythrocytes.
In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells. .
|Sequence:||1; NC_000001.11 (116500390..116571093, complement)|
[Isoform 1]: Cell membrane; Single-pass type I membrane protein.