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- Table of Contents
CD58 Antibodies
AND CD58 ELISA kits, CD58 Proteins
Many biological assays use antibodies to detect CD58, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CD58 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CD58 antibodies...
Designing a Western blot for CD58? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the CD58 Western Blot GuideCD58 Infographic by Boster Bio
All CD58 Products
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CD58 Overview
Facts about Lymphocyte function-associated antigen 3.
Lymphocyte function-associated antigen 3 (CD58)
Ligand of the T-lymphocyte CD2 glycoprotein.
This interaction is important in mediating thymocyte interactions with thymic epithelial cells, antigen-independent and -dependent interactions of T-lymphocytes with target cells and antigen- presenting cells and the T-lymphocyte rosetting with erythrocytes.In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells. .
Gene Information
| Human | |
|---|---|
| Gene Name: | CD58 |
| Uniprot: | P19256 |
| Entrez: | 965 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
Ag3; CD58 antigen; CD58 antigen, (lymphocyte function-associated antigen 3); CD58 molecule; CD58; FLJ23181; FLJ43722; LFA3; LFA-3; LFA3ag3; lymphocyte function-associated antigen 3; Surface glycoprotein LFA-3
Molecular Weight
Mass (kDA):
28.147 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1p13.1 |
| Sequence: | 1; NC_000001.11 (116500390..116571093, complement) |
Subcellular Localizations
[Isoform 1]: Cell membrane; Single-pass type I membrane protein.
Diseases
- Tissue Adhesions
- Neoplasms
- Leukemia
- Malignant Neoplasms
- Carcinoma
- Malignant Paraganglionic Neoplasm
- Inflammation
- Lymphoma
- Leukemia, Myelocytic, Acute
- Myeloid Leukemia
- Acute Lymphocytic Leukemia
- Autoimmune Reaction
- Sclerosis
Pathways
- Cell Adhesion
- Cell Activation
- T Cell Activation
- Immune Response
- Cell Proliferation
- Secretion
- Pathogenesis
- T Cell Proliferation
- Cytokine Production
- Cytolysis
- Lymphocyte Activation
- Cell-cell Adhesion
- Cell Growth
PTMs
- Phosphorylation
- Glycosylation
- Biotinylation
- Cleavage
- Deglycosylation
Research Areas
- Cell Biology
- Cellular Markers
- Immunology
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CD58
bosterbio.com/bosterbio-gene-info-cards/CD58
References
PMID: 3309127 by Wallner B.P., et al. Primary structure of lymphocyte function-associated antigen 3 (LFA- 3). The ligand of the T lymphocyte CD2 glycoprotein.
PMID: 3313052 by Seed B.; An LFA-3 cDNA encodes a phospholipid-linked membrane protein homologous to its receptor CD2.