This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
CDCP1 Antibodies
AND CDCP1 ELISA kits, CDCP1 Proteins
Many biological assays use antibodies to detect CDCP1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CDCP1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CDCP1 antibodies...
Previous: Septin9
Next: PCDH20
CDCP1 Infographic by Boster Bio
All CDCP1 Products
Product
Figures
Specificity
Applications
Price
Anti-CDCP1 Antibody Picoband®
2 Citations 4 Q&As
Human, Mouse, Rat
Flow Cytometry, IHC, WB
$370
Cat # PB9933
100 μg/vial
Cat # PB9933
100 μg/vial
Human CDCP1 ELISA Kit PicoKine®
11 Q&As
Human
ELISA
$750
Cat # EK1668
96 wells/kit, with removable strips.
Cat # EK1668
96 wells/kit, with removable strips.
Dog, Human, Monkey, Mouse
Flow Cytometry, WB
$523
Cat # M02411-1
100 µl
Cat # M02411-1
100 µl
Human
Flow Cytometry, IF, IHC, WB
$523
Cat # M02411
100 µl
Cat # M02411
100 µl
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M02411-3
100 μg
Cat # M02411-3
100 μg
Cynomolgus monkey, Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M02411-4
100 μg
Cat # M02411-4
100 μg
CDCP1 Overview
Facts about CUB domain-containing protein 1.
CUB domain-containing protein 1 (CDCP1)
May be involved in cell adhesion and cell matrix institution. May play a role in the regulation of anchorage versus migration or proliferation versus differentiation through its phosphorylation.
May be a novel marker for leukemia diagnosis and for immature hematopoietic stem cell subsets. Belongs to the tetraspanin web involved in tumor progression and metastasis.
Gene Information
| Human | |
|---|---|
| Gene Name: | CDCP1 |
| Uniprot: | Q9H5V8 |
| Entrez: | 64866 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
CD318 antigen; CD318; CDCP1; CUB domain containing protein 1; CUB domain-containing protein 1; Membrane glycoprotein gp140; SIMA135; SIMA135TRASK; Subtractive immunization M plus HEp3-associated 135 kDa protein; Transmembrane and associated with src kinases
Molecular Weight
Mass (kDA):
92.932 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 3p21.31 |
| Sequence: | 3; NC_000003.12 (45082277..45146422, complement) |
Tissue Specificity
Highly expressed in mitotic cells with low expression during interphase. Detected at highest levels in skeletal muscle and colon with lower levels in kidney, small intestine, placenta and lung. Up-regulated in a number of human tumor cell lines, as well as in colorectal cancer, breast carcinoma and lung cancer. Also expressed in cells with phenotypes reminiscent of mesenchymal stem cells and neural stem cells.
Subcellular Localizations
[Isoform 1]: Cell membrane; Single-pass membrane protein. Shedding may also lead to a soluble peptide.; [Isoform 3]: Secreted.
Diseases
- Malignant Neoplasms
- Neoplasms
- Neoplasm Metastasis
- Tissue Adhesions
- Carcinoma
- Cell Invasion
- Prostatic Neoplasms
- Malignant Neoplasm Of Prostate
- Neoplasm Invasiveness
- Adenocarcinoma
- Mammary Neoplasms
- Colonic Neoplasms
Interacting Proteins
- SDCBP
- SRC
- YES1
Pathways
- Cell Migration
- Cell Adhesion
- Mitosis
- Anoikis
- Transport
- Cell Motility
- Interphase
- Cell Proliferation
- Methylation
- Rna Interference
- Protein Phosphorylation
- Hyperphosphorylation
- Proteolysis
PTMs
- Phosphorylation
- Cleavage
- Demethylation
Research Areas
- Phospho-Specific
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CDCP1
bosterbio.com/bosterbio-gene-info-cards/CDCP1
References
PMID: 11466621 by Scherl-Mostageer M., et al. Identification of a novel gene, CDCP1, overexpressed in human colorectal cancer.
PMID: 12660814 by Hooper J.D., et al. Subtractive immunization using highly metastatic human tumor cells identifies SIMA135/CDCP1, a 135 kDa cell surface phosphorylated glycoprotein antigen.