CDK2AP2 Antibodies

AND CDK2AP2 ELISA kits, CDK2AP2 Proteins

Many biological assays use antibodies to detect CDK2AP2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CDK2AP2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CDK2AP2 antibodies...

We validate the specificity of these antibodies to CDK2AP2 by testing them on tissues known to express CDK2AP2 positively and negatively. Browse below to find the CDK2AP2 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CDK2AP2 Infographic by Boster Bio

All CDK2AP2 Products

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Specificity

Applications

Price

CDK2AP2 (NM_005851) Human Recombinant Protein

Coomassie blue staining of purified CDK2AP2 protein

$1249
Cat # PROTO75956
20 µg

CDK2AP2 (NM_005851) Human Over-expression Lysate

Human

$628
Cat # LS010263
20 µg, 100 µg

Anti-CDK2AP2 Antibody

Human

ELISA, WB

$370
Cat # A14813-1
100 μl/vial

CDK2AP2 Overview

Facts about Cyclin-dependent kinase 2-associated protein 2.

CDK2AP2 3D structure. Source: alphafold

Cyclin-dependent kinase 2-associated protein 2 (CDK2AP2)

Plays a role in regulating the self-renewal of embryonic stem cells (ESCs) and in maintaining cell survival during terminal differentiation of ESCs. Regulates microtubule organization of metaphase II oocytes (By similarity).

Inhibits cell cycle G1/S phase transition from repressing CDK2 expression and activation; represses CDK2 activation by inhibiting its interaction with cyclin E and A (PubMed:23781148). .

Gene Information

Human
Gene Name:	CDK2AP2
Uniprot:	O75956
Entrez:	10263

Family

Belongs to:

CDK2AP family

Alternative Names

CDK2-associated protein 2tumor suppressor deleted in oral cancer related 1; cyclin-dependent kinase 2 associated protein 2; DOC1R; DOC-1Rcyclin-dependent kinase 2-associated protein 2; DOC-1-related protein; FLJ10636; p14; tumor suppressor deleted in oral cancer-related 1

Molecular Weight

Mass (kDA):
13.101 kDA

Genomic Context


Human

Location:	11q13.2
Sequence:	11; NC_000011.10 (67506497..67508162, complement)

Tissue Specificity

Ubiquitous.

Subcellular Localizations

Cytoplasm. Nucleus. Accumulates in immature oocytes in the nucleus. During the first meiotic division, accumulates in the cytoplasm and localizes in dots in the vicinity of the chromosomes in a region enriched in microtubules.

Diseases

Immunologic Deficiency Syndromes
Teratoma
Severe Combined Immunodeficiency
Leukemia
Congenital Combined Immunodeficiency

Pathways

Bioluminescence
Reverse Transcription
Stem Cell Differentiation
Cell Differentiation

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CDK2AP2

References

PMID: 10082655 by Zhang X., et al. Identification and mutation analysis of DOC-1R, a DOC-1 growth suppressor-related gene.

PMID: 14985111 by Buajeeb W., et al. Interaction of the CDK2-associated protein-1, p12(DOC-1/CDK2AP1), with its homolog, p14(DOC-1R).