RAMP2 Antibodies

AND RAMP2 ELISA kits, RAMP2 Proteins

Many biological assays use antibodies to detect RAMP2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RAMP2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RAMP2 antibodies...

We validate the specificity of these antibodies to RAMP2 by testing them on tissues known to express RAMP2 positively and negatively. Browse below to find the RAMP2 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for RAMP2? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the RAMP2 Western Blot Guide

RAMP2 Infographic by Boster Bio

All RAMP2 Products

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Applications

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RAMP2 (NM_005854) Human Over-expression Lysate

Human

$628
Cat # LS010266
20 µg, 100 µg

Anti-RAMP2 Antibody

Western blot analysis of extracts of various cell lines, using RAMP2 antibody at 1:1000 dilution

Immunohistochemistry of paraffin-embedded human breast cancer using RAMP2 Rabbit pAb at dilution of 1:200

Immunohistochemistry of paraffin-embedded human esophageal cancer using RAMP2 Rabbit pAb at dilution of 1:200

Human, Mouse, Rat

IHC, WB

$405
Cat # A04768
100ul

RAMP2 Overview

Facts about Receptor activity-modifying protein 2.

RAMP2 3D structure. Source: alphafold

Receptor activity-modifying protein 2 (RAMP2)

Transports that the calcitonin gene-related peptide type 1 receptor (CALCRL) into the plasma membrane. Acts as a receptor for adrenomedullin (AM) together with CALCRL.

Gene Information

Human
Gene Name:	RAMP2
Uniprot:	O60895
Entrez:	10266

Family

Belongs to:

RAMP family

Alternative Names

calcitonin receptor-like receptor activity modifying protein 2; Calcitonin-receptor-like receptor activity-modifying protein 2; CRLR activity-modifying protein 2; RAMP2; receptor (calcitonin) activity modifying protein 2; receptor (G protein-coupled) activity modifying protein 2; receptor activity modifying protein 2; receptor activity-modifying protein 2; receptor-activity-modifying protein 2

Molecular Weight

Mass (kDA):
19.608 kDA

Genomic Context


Human

Location:	17q21.2
Sequence:	17; NC_000017.11 (42761227..42763041)

Tissue Specificity

Strongly expressed in lung, breast, immune system and fetal tissues.

Subcellular Localizations

Membrane; Single-pass type I membrane protein.

Diseases

Hypertensive Disease
Neoplasms
Hypertrophy
Hypoxia
Tumor Angiogenesis
Heart Failure
Malignant Neoplasms
Pheochromocytoma
Cardiovascular Diseases
Pathologic Neovascularization
Myocardial Infarction
Anoxia

Ischemia
Disease Of Adrenal Medulla
Fibrosis
Pulmonary Hypertension
Malignant Paraganglionic Neoplasm
Myocardial Ischemia

Interacting Proteins

CALCRL

Pathways

Transport
Secretion
Cell Proliferation
Angiogenesis
Pathogenesis
Localization
Glycosylation
Reverse Transcription
Vasodilation
Receptor Internalization
Rna Interference
Excretion
Cell Migration

Testosterone Secretion
Dna Methylation
Ovulation
Gene Silencing
Lymphangiogenesis
Diuresis
Inflammatory Response

PTMs

Glycosylation
Amidation
Phosphorylation
Cleavage

Oxidation
Methylation
Reduction
Acetylation

Iodination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RAMP2

References

PMID: 9620797 by McLatchie L.M., et al. RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor.

PMID: 22102369 by Kusano S., et al. Structural basis for extracellular interactions between calcitonin receptor-like receptor and receptor activity-modifying protein 2 for adrenomedullin-specific binding.