CEP170 Antibodies

AND CEP170 ELISA kits, CEP170 Proteins

Many biological assays use antibodies to detect CEP170, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CEP170 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CEP170 antibodies...

We validate the specificity of these antibodies to CEP170 by testing them on tissues known to express CEP170 positively and negatively. Browse below to find the CEP170 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CEP170 Infographic by Boster Bio

All CEP170 Products

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Anti-Centrosomal protein of 170 kDa CEP170 Antibody

4 Q&As

Western Blot analysis of various cells using CEP170 Polyclonal Antibody diluted at 1:1000

Western Blot analysis of AD293 cells using CEP170 Polyclonal Antibody diluted at 1:1000

Western blot analysis of lysates from HepG2 and Jurkat cells, using CEP170 Antibody

Human, Mouse

ELISA, IF, IHC, WB

$399
Cat # A08211
100μl

Anti-Centrosomal protein of 170 kDa CEP170 Antibody

1 Q&As

Immunohistochemistry analysis of paraffin-embedded human testis tissue, using CEP170 Antibody

Human, Mouse, Rat

ELISA, IF, IHC, ICC, WB

$335
Cat # A30606
100ul

Anti-CEP170 Antibody

Human

ELISA, IF, ICC, WB

$370
Cat # A08211-1
100 μl/vial

CEP170 Overview

Facts about Centrosomal protein of 170 kDa.

CEP170 3D structure. Source: alphafold

Centrosomal protein of 170 kDa (CEP170)

Plays a role in microtubule organization (PubMed:15616186). Required for centriole subdistal appendage assembly (PubMed:28422092).

Gene Information

Human
Gene Name:	CEP170
Uniprot:	Q5SW79
Entrez:	9859

Family

Belongs to:

CEP170 family

Alternative Names

centrosomal protein 170kDa; Cep170; KARP 1 binding protein; KARP-1-binding protein; KARP1-binding protein; KIAA0470FAM68AKABcentrosomal protein of 170 kDa; XRCC5 binding protein

Molecular Weight

Mass (kDA):
175.293 kDA

Genomic Context


Human

Location:	1q43
Sequence:	1; NC_000001.11 (243124428..243255796, complement)

Subcellular Localizations

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, spindle. Associated with the mature mother centriole. Associated with spindle microtubules during mitosis. Localizes to the distal appendage region of the centriole.

Diseases

Neoplasms
Malignant Neoplasm Of Breast
Malignant Neoplasms
Mammary Neoplasms
Congenital Absence
Microcephaly
Malignant Squamous Cell Neoplasm
Cell Transformation, Neoplastic
Genomic Instability
Malignant Paraganglionic Neoplasm
Aneuploidy

Anus Neoplasms
Hypoplasia
Impaired Cognition
Smith-magenis Syndrome
Agenesis Of Corpus Callosum

Interacting Proteins

CCDC120
CCDC68
DISC1

Pathways

Cell Division
Mitosis
Interphase
Microtubule Depolymerization
G2 Phase
Cell Cycle
Centrosome Duplication
Pathogenesis

Chromosome Segregation
Localization

PTMs

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CEP170

References

PMID: 15616186 by Guarguaglini G., et al. The forkhead-associated domain protein Cep170 interacts with Polo- like kinase 1 and serves as a marker for mature centrioles.

PMID: 23386061 by Kodani A., et al. Kif3a interacts with Dynactin subunit p150 Glued to organize centriole subdistal appendages.