CHD4 Antibodies

AND CHD4 ELISA kits, CHD4 Proteins

Many biological assays use antibodies to detect CHD4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CHD4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CHD4 antibodies...

We validate the specificity of these antibodies to CHD4 by testing them on tissues known to express CHD4 positively and negatively. Browse below to find the CHD4 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for CHD4? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the CHD4 Western Blot Guide

CHD4 Infographic by Boster Bio

All CHD4 Products

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Product

Figures

Specificity

Applications

Price

Anti-CHD4 Antibody Picoband®

Western blot analysis of CHD4 using anti-CHD4 antibody (A01125-3)

Flow Cytometry analysis of MCF-7 cells using anti-CHD4 antibody (A01125-3)

Human

Flow Cytometry, WB

$370
Cat # A01125-3
100 μg/vial

Anti-CHD4 Rabbit Monoclonal Antibody

Western blot analysis of CHD4 expression in 293T cell lysate

Human

Flow Cytometry, IF, ICC, WB

$370
Cat # M01125
100 μl

Anti-CHD4 antibody

Human

ELISA, IP, IF, IHC, ICC, WB

$370
Cat # A01125-2
100 μl/vial

CHD4 Overview

Facts about Chromodomain-helicase-DNA-binding protein 4.

CHD4 3D structure. Source: alphafold

Chromodomain-helicase-DNA-binding protein 4 (CHD4)

Component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin by deacetylating histones. .

Gene Information

Human
Gene Name:	CHD4
Uniprot:	Q14839
Entrez:	1108

Family

Belongs to:

SNF2/RAD54 helicase family

Alternative Names

ATP-dependent helicase CHD4; CHD-4; chromodomain helicase DNA binding protein 4; chromodomain-helicase-DNA-binding protein 4; DKFZp686E06161; EC 3.6.1; EC 3.6.4.12; Mi-2 autoantigen 218 kDa protein; Mi-2b; Mi2-BETA

Molecular Weight

Mass (kDA):
218.005 kDA

Genomic Context


Human

Location:	12p13.31
Sequence:	12; NC_000012.12 (6570082..6607379, complement)

Subcellular Localizations

Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Associates with centrosomes in interphase.

Diseases

Dermatomyositis
Malignant Neoplasms
Neoplasms
Neoplasm Metastasis
Polymyositis
Myositis
Myopathy
Autoimmune Reaction
Myopathy, Idiopathic Inflammatory
Arthritis
Cell Transformation, Neoplastic
Malignant Tumor Of Cervix

Mammary Neoplasms
Liver Carcinoma
Autoimmune Diseases
Ataxia Telangiectasia
Arthralgia
Osteosarcoma
Neuroblastoma

Interacting Proteins

HDAC1
MYC
Tbx5
ZNF827

Pathways

Chromatin Remodeling
Methylation
Histone Deacetylation
Dna Methylation
Dna Repair
Cell Cycle
Rna Interference
Histone Acetylation
Cell Proliferation
Dna Replication
Pathogenesis
Atp-dependent Chromatin Remodeling
Myelination

Cell Differentiation
S Phase
Chromatin Assembly
Gene Silencing
Localization
Histone Modification
Regeneration

PTMs

Deacetylation
Methylation
Phosphorylation

Acetylation
Demethylation
Sumoylation

Reduction

Research Areas

Immune System Diseases
Immunology

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CHD4

References

PMID: 7575689 by Seelig H.P., et al. The major dermatomyositis specific Mi-2 autoantigen is a presumed helicase involved in transcriptional activation.

PMID: 9804427 by Tong J.K., et al. Chromatin deacetylation by an ATP-dependent nucleosome remodelling complex.