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- Table of Contents
Chromogranin-A Antibodies
AND CHGA ELISA kits, Chromogranin-A Proteins
Many biological assays use antibodies to detect Chromogranin-A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Chromogranin-A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Chromogranin-A antibodies...
Designing a Western blot for Chromogranin-A? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the CHGA Western Blot GuideCHGA Infographic by Boster Bio
All CHGA Products
Product
Figures
Specificity
Applications
Price
Anti-Chromogranin A/Chga Antibody Picoband®
1 Citations
Mouse, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A01256-2
100 μg/vial
Cat # A01256-2
100 μg/vial
Human
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A01256-4
100 µg/vial
Cat # A01256-4
100 µg/vial
Human
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M01256-1
100 μl
Cat # M01256-1
100 μl
Human, Mouse
IF, IHC, WB
$523
Cat # M01256-2
100 µl
Cat # M01256-2
100 µl
Human, Mouse, Rat
ELISA, IP, IF, IHC, WB
$146
Cat # M01256-3
20μL, 40μL, 100μL, 200μL
Cat # M01256-3
20μL, 40μL, 100μL, 200μL
Human
$628
Cat # LS001113
20 µg, 100 µg
Cat # LS001113
20 µg, 100 µg
CHGA Overview
Facts about Chromogranin-A.
Chromogranin-A (CHGA)
Pancreastatin: Strongly inhibits glucose induced insulin release from the pancreas. .
Gene Information
| Human | |
|---|---|
| Gene Name: | CHGA |
| Uniprot: | P10645 |
| Entrez: | 1113 |
Family
| Belongs to: |
|---|
| chromogranin/secretogranin protein family |
Alternative Names
betagranin (N-terminal fragment of chromogranin A); Betagranin; Catestatin; CGA; CHGA; Chromofungin; chromogranin A (parathyroid secretory protein 1); Chromogranin A; chromogranin-A; Pancreastatin; Parastatin; Parathyroid Secretory Protein 1; Pituitary Secretory Protein I; SP-I
Molecular Weight
Mass (kDA):
50.688 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 14q32.12 |
| Sequence: | 14; NC_000014.9 (92922594..92935293) |
Tissue Specificity
GE-25 is found in the brain.
Subcellular Localizations
[Serpinin]: Secreted. Cytoplasmic vesicle, secretory vesicle. Pyroglutaminated serpinin localizes to secretory vesicle.; Cytoplasmic vesicle, secretory vesicle. Cytoplasmic vesicle, secretory vesicle, neuronal dense core vesicle. Secreted. Associated with the secretory granule membrane through direct interaction to SCG3 that in turn binds to cholesterol-enriched lipid rafts in intragranular conditions. In pituitary gonadotropes, located in large secretory granules.
Diseases
- Neoplasms
- Carcinoma
- Neuroendocrine Tumors
- Malignant Neoplasms
- Pheochromocytoma
- Carcinoid Tumor
- Hypertensive Disease
- Prostatic Neoplasms
- Malignant Neoplasm Of Prostate
- Pituitary Diseases
- Neoplasm Metastasis
- Lung Neoplasms
- Adenocarcinoma
Pathways
- Secretion
- Localization
- Exocytosis
- Catecholamine Secretion
- Pathogenesis
- Secretory Pathway
- Hormone Secretion
- Regulated Secretory Pathway
- Cell Proliferation
- Proteolysis
- Glomerular Filtration
- Cell Differentiation
- Excretion
PTMs
- Cleavage
- Phosphorylation
- Glycosylation
- Amidation
- Methylation
Research Areas
- Cancer
- Neuronal Cell Markers
- Tumor Biomarkers
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CHGA
bosterbio.com/bosterbio-gene-info-cards/CHGA
References
PMID: 2445752 by Konecki D.S., et al. The primary structure of human chromogranin A and pancreastatin.
PMID: 3403545 by Helman L.J., et al. Molecular cloning and primary structure of human chromogranin A (secretory protein I) cDNA.
1 Publications of Boster Chromogranin-A Antibodies & ELISA Kits
- PubMed ID: 31732520, Glumac PM,Gallant JP,Shapovalova M,Li Y,Murugan P,Gupta S,Coleman IM,Nelson PS,D...
*More publications can be found for each product on its corresponding product page