CHRM3 Antibodies

AND CHRM3 ELISA kits, CHRM3 Proteins

Many biological assays use antibodies to detect CHRM3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CHRM3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CHRM3 antibodies...

We validate the specificity of these antibodies to CHRM3 by testing them on tissues known to express CHRM3 positively and negatively. Browse below to find the CHRM3 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for CHRM3? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the CHRM3 Western Blot Guide

CHRM3 Infographic by Boster Bio

All CHRM3 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-Muscarinic Acetylcholine Receptor M3 Rabbit Monoclonal Antibody

1 Citations

Human

$370
Cat # M03150
100 μl/vial

Muscarinic Acetylcholine Receptor M3 (CHRM3) (NM_000740) Human Over-expression Lysate

Human

$960
Cat # LS001131
20 µg, 100 µg

CHRM3 Overview

Facts about Muscarinic acetylcholine receptor M3.

CHRM3 3D structure. Source: alphafold

Muscarinic acetylcholine receptor M3 (CHRM3)

The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.

Gene Information

Human
Gene Name:	CHRM3
Uniprot:	P20309
Entrez:	1131

Family

Belongs to:

G-protein coupled receptor 1 family

Alternative Names

cholinergic receptor, muscarinic 3; CHRM3; HM3; m3 muscarinic receptor; mAChR M3; muscarinic acetylcholine receptor M3

Molecular Weight

Mass (kDA):
66.128 kDA

Genomic Context


Human

Location:	1q43
Sequence:	1; NC_000001.11 (239386565..239915450)

Subcellular Localizations

Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Colocalizes with TMEM147 in the endoplasmic reticulum (ER) membrane. TMEM147 impairs its trafficking to the cell membrane leading to its retention in the ER membrane.

Diseases

Malignant Neoplasms
Epilepsy
Sclerosis
Malignant Tumor Of Colon
Scleral Diseases
Neoplasms
Bronchial Hyperreactivity
Diabetes Mellitus
Myopia
Inflammation
Nervousness
Asthma
Nausea And Vomiting

Nausea
Malignant Neoplasm Of Stomach
Obesity
Vomiting
Stomach Neoplasms
Neoplasm Metastasis
Adenoma

Interacting Proteins

CHRM5
NALCN

Pathways

Secretion
Pathogenesis
Gastric Acid Secretion
Acid Secretion
Cell Adhesion
Transport
Cell Migration
Cell Proliferation
Insulin Secretion
Hepatocyte Proliferation

Fermentation
Reverse Transcription
System Development
Nervous System Development

PTMs

Cleavage

Research Areas

GPCR

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CHRM3

References

PMID: 3443095 by Peralta E.G., et al. Distinct primary structures, ligand-binding properties and tissue- specific expression of four human muscarinic acetylcholine receptors.

PMID: 3272174 by Bonner T.I., et al. Cloning and expression of the human and rat m5 muscarinic acetylcholine receptor genes.