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, No Gclids
CLCN7 Antibodies
AND CLCN7 ELISA kits, CLCN7 Proteins
Many biological assays use antibodies to detect CLCN7, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CLCN7 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CLCN7 antibodies...
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CLCN7 Overview
Facts about H(+)/Cl(-) exchange transporter 7.
H(+)/Cl(-) exchange transporter 7 (CLCN7)
Gradually voltage-gated channel mediating the exchange of chloride ions against protons. Functions as antiporter and contributes to the acidification of the lysosome lumen.
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Gene Information
| Human | |
|---|---|
| Gene Name: | CLCN7 |
| Uniprot: | P51798 |
| Entrez: | 1186 |
Family
| Belongs to: |
|---|
| chloride channel (TC 2.A.49) family |
Alternative Names
H(+)/Cl(-) exchange transporter 7
Molecular Weight
Mass (kDA):
88.679 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 16p13.3 |
| Sequence: | 16; NC_000016.10 (1444933..1475084, complement) |
Tissue Specificity
Brain, testis, muscle and kidney.
Subcellular Localizations
Lysosome membrane; Multi-pass membrane protein.
Diseases
- Osteopetrosis, autosomal recessive 4 (OPTB4)
PTMs
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CLCN7
bosterbio.com/bosterbio-gene-info-cards/CLCN7
References
PMID: 8543009 by Brandt S., et al. ClC-6 and ClC-7 are two novel broadly expressed members of the CLC chloride channel family.
PMID: 9565675 by Eggermont J.; The exon-intron architecture of human chloride channel genes is not conserved.