CLN6 Antibodies

AND CLN6 ELISA kits, CLN6 Proteins

Many biological assays use antibodies to detect CLN6, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CLN6 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CLN6 antibodies...

We validate the specificity of these antibodies to CLN6 by testing them on tissues known to express CLN6 positively and negatively. Browse below to find the CLN6 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for CLN6? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the CLN6 IHC Guide

CLN6 Infographic by Boster Bio

All CLN6 Products

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Product

Figures

Specificity

Applications

Price

Anti-CLN6 (N258) Antibody

Western blot (WB) analysis of CLN6 (N258) pAb at 1:500 dilution
Lane1:SGC7901 whole cell lysate(40ug)
Lane2:SK-OVCAR3 whole cell lysate(40ug)
Lane3:MCF-7 whole cell lysate(40ug)
Lane4:PC12 whole cell lysate(40ug)
Lane5:CT26 whole cell lysate(40ug)

Immunohistochemistry (IHC) analyzes of CLN6 (N258) pAb in paraffin-embedded human stomach carcinoma tissue at 1:50

Human, Mouse, Rat

IHC, WB

$405
Cat # A03538
100ul

CLN6 (NM_017882) Human Over-expression Lysate

Human

$628
Cat # LS054982
20 µg, 100 µg

CLN6 (NM_017882) Human Recombinant Protein

Coomassie blue staining of purified CLN6 protein

$1249
Cat # PROTQ9NWW5
20 µg

CLN6 Overview

Facts about Ceroid-lipofuscinosis neuronal protein 6.

CLN6 3D structure. Source: alphafold

Ceroid-lipofuscinosis neuronal protein 6 (CLN6)

Gene Information

Human
Gene Name:	CLN6
Uniprot:	Q9NWW5
Entrez:	54982

Family

Belongs to:

No superfamily

Alternative Names

ceroid-lipofuscinosis neuronal protein 6; ceroid-lipofuscinosis, neuronal 6, late infantile, variant; FLJ20561; HsT18960; nclf; Protein CLN6

Molecular Weight

Mass (kDA):
35.919 kDA

Genomic Context


Human

Location:	15q23
Sequence:	15; NC_000015.10 (68206992..68229728, complement)

Subcellular Localizations

Endoplasmic reticulum membrane; Multi-pass membrane protein. Endoplasmic reticulum.

Diseases

Neuronal Ceroid-lipofuscinoses
Neurodegenerative Disorders
Late-infantile Neuronal Ceroid Lipfuscinosis
Nerve Degeneration
Juvenile Neuronal Ceroid Lipfuscinosis
Epilepsy
Lysosomal Storage Diseases
Blind Vision
Infantile Neuronal Ceroid Lipofuscinosis
Ceroid Lipofuscinosis, Neuronal, 5
Atrophy
Dementia

Nervousness
Visual Impairment
Cerebral Atrophy
Epilepsies, Myoclonic
Myoclonus
Adult Neuronal Ceroid Lipofuscinosis

Pathways

Pathogenesis
Localization
Cell Death
Transport
Cell Activation
Glycosylation
Cell Growth
Response To Anoxia
Cell Proliferation
Gene Silencing
Brain Development
Fertilization
Astrocyte Activation

Endocytosis
Oxidative Phosphorylation
Ovulation
Lysosomal Transport
Neuron Death
Inflammatory Response
Neuroprotection

PTMs

Glycosylation

Phosphorylation

Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CLN6

References

PMID: 15265688 by Mole S.E., et al. CLN6, which is associated with a lysosomal storage disease, is an endoplasmic reticulum protein.

PMID: 19941651 by Lyly A., et al. Novel interactions of CLN5 support molecular networking between neuronal ceroid lipofuscinosis proteins.