Cochlin Antibodies

AND COCH ELISA kits, Cochlin Proteins

Many biological assays use antibodies to detect Cochlin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Cochlin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Cochlin antibodies...

We validate the specificity of these antibodies to Cochlin by testing them on tissues known to express COCH positively and negatively. Browse below to find the COCH antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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COCH Infographic by Boster Bio

All COCH Products

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Product

Figures

Specificity

Applications

Price

Anti-Cochlin COCH Antibody

Western blot analysis of COCH expression in HEK293T (A) whole cell lysates

Immunofluorescent analysis of COCH staining in HeLa cells

Human

IF, IHC, ICC

$405
Cat # A04411
100ul

Human Cochlin ELISA Kit PicoKine®

Human

ELISA

$499
Cat # EK2306
96 wells/kit, with removable strips.

COCH Overview

Facts about Cochlin.

COCH 3D structure. Source: alphafold

Cochlin (COCH)

Plays a role in the control of cell shape and motility in the trabecular meshwork. .

Gene Information

Human
Gene Name:	COCH
Uniprot:	O43405
Entrez:	1690

Family

Belongs to:

No superfamily

Alternative Names

coagulation factor C (Limulus polyphemus homolog); cochlin; coagulation factor C homolog, cochlin (Limulus polyphemus); COCH; COCH5B2; COCH-5B2COCH5B2; Cochlin; DFNA31; DFNA9

Molecular Weight

Mass (kDA):
59.483 kDA

Genomic Context


Human

Location:	14q12
Sequence:	14; NC_000014.9 (30874496..30890618)

Tissue Specificity

Expressed in inner ear structures; the cochlea and the vestibule.

Subcellular Localizations

Secreted, extracellular space, extracellular matrix.

Diseases

Sensorineural Hearing Loss (disorder)
Complete Hearing Loss
Vestibular Diseases
Meniere Disease
Vertigo
Glaucoma
Cochlear Diseases
Presbycusis
Intraocular Pressure Disorder
Hearing Problem
Columnar Cell Hyperplasia Of The Breast
Von Willebrand Disease

Tuberculosis
Autoimmune Diseases
Aqueous Humor Disorders
Autoimmune Reaction
Glaucoma, Open-angle
Labyrinthine Disorder
Cholangiocarcinoma

Pathways

Coagulation
Pathogenesis
Localization
Secretion
Reflex
Dehiscence
Transport
Cell Adhesion
Flower Development
Photosynthesis
Aging
Proteolysis
Immune Response

Inner Ear Development
Spermatogenesis
Transepithelial Transport
Embryo Implantation
Drug Transport
Secretory Pathway
Glycosylation

PTMs

Oxidation
Nitration
Carboxylation

Glycosylation
Cleavage
Decarboxylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/COCH

References

PMID: 9441737 by Robertson N.G., et al. Mapping and characterization of a novel cochlear gene in human and in mouse: a positional candidate gene for a deafness disorder, DFNA9.

PMID: 12843317 by Robertson N.G., et al. Subcellular localisation, secretion, and post-translational processing of normal cochlin, and of mutants causing the sensorineural deafness and vestibular disorder, DFNA9.