Collagen alpha-3(V) chain Antibodies

AND COL5A3 ELISA kits, Collagen alpha-3(V) chain Proteins

Many biological assays use antibodies to detect Collagen alpha-3(V) chain, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Collagen alpha-3(V) chain in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Collagen alpha-3(V) chain antibodies...

We validate the specificity of these antibodies to Collagen alpha-3(V) chain by testing them on tissues known to express COL5A3 positively and negatively. Browse below to find the COL5A3 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for Collagen alpha-3(V) chain? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the COL5A3 Western Blot Guide

Designing an IHC experiment for Collagen alpha-3(V) chain? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the COL5A3 IHC Guide

COL5A3 Infographic by Boster Bio

All COL5A3 Products

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Anti-Collagen alpha-3(V) chain COL5A3 Antibody

Western Blot analysis of various cells using COL5A3 Polyclonal Antibody

Western Blot analysis of K562 cells using COL5A3 Polyclonal Antibody

Human

ELISA, IF, IHC, WB

$399
Cat # A10525
100μl

Collagen V (COL5A3) (NM_015719) Human Over-expression Lysate

Human

$960
Cat # LS050509
20 µg, 100 µg

COL5A3 Overview

Facts about Collagen alpha-3(V) chain.

COL5A3 3D structure. Source: alphafold

Collagen alpha-3(V) chain (COL5A3)

Type V collagen is a member of group I collagen (fibrillar forming collagen). It is a minor connective tissue component of nearly ubiquitous distribution.

Type V collagen binds to DNA, heparan sulfate, thrombospondin, heparin, and insulin. .

Gene Information

Human
Gene Name:	COL5A3
Uniprot:	P25940
Entrez:	50509

Family

Belongs to:

fibrillar collagen family

Alternative Names

collagen alpha-3(V) chain; collagen, type V, alpha 3; pro-(alpha)3(V) collagen

Molecular Weight

Mass (kDA):
172.121 kDA

Genomic Context


Human

Location:	19p13.2
Sequence:	19; NC_000019.10 (9959561..10010532, complement)

Subcellular Localizations

Secreted, extracellular space, extracellular matrix.

Diseases

Ehlers-danlos Syndrome
Joint Laxity
Fibrosis
Hypertensive Disease
Disease Of Adrenal Medulla
Collagen Diseases
Stenosis
Pulmonary Valve Stenosis
Injury To Kidney
Osteosarcoma
Pain
Pulmonary Hypertension

Cicatrix
Hereditary Diseases
Stricture Of Artery
Diabetes Mellitus
Connective Tissue Diseases
Crest Syndrome

Pathways

Osteoblast Differentiation
Glucose Homeostasis
Cell Proliferation
Insulin Secretion
Regulation Of Osteoblast Differentiation
Wound Healing
Positive Regulation Of Osteoblast Differentiation

Secretion

PTMs

Disulfide bond

Glycoprotein

Hydroxylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/COL5A3

References

PMID: 10722718 by Imamura Y., et al. The pro-alpha3 (V) collagen chain. Complete primary structure, expression domains in adult and developing tissues, and comparison to the structures and expression domains of the other types V and XI procollagen chains.

PMID: 1571108 by Mann K.; Isolation of the alpha 3-chain of human type V collagen and characterization by partial sequencing.