This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Coronin-1A Antibodies
AND CORO1A ELISA kits, Coronin-1A Proteins
Many biological assays use antibodies to detect Coronin-1A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Coronin-1A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Coronin-1A antibodies...
Designing a Western blot for Coronin-1A? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the CORO1A Western Blot GuideDesigning an IHC experiment for Coronin-1A? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the CORO1A IHC GuideCORO1A Infographic by Boster Bio
All CORO1A Products
Product
Figures
Specificity
Applications
Price
Anti-Coronin 1a/TACO/CORO1A Antibody Picoband®
1 Citations
Human, Mouse, Rat
ELISA, Flow Cytometry, IP, IHC, WB
$370
Cat # A04245-2
100 μg/vial
Cat # A04245-2
100 μg/vial
CORO1A Overview
Facts about Coronin-1A.
Coronin-1A (CORO1A)
May be a crucial part of the cytoskeleton of highly motile cells, working both in the invagination of big pieces of plasma membrane, as well as in forming protrusions of the plasma membrane involved in cell locomotion. In mycobacteria- infected cells, its retention on the phagosomal membrane prevents fusion between phagosomes and lysosomes.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | CORO1A |
| Uniprot: | P31146 |
| Entrez: | 11151 |
Family
| Belongs to: |
|---|
| WD repeat coronin family |
Alternative Names
CLIPINA; clipin-A; CORO1; coronin, actin binding protein, 1A; coronin, actin-binding protein, 1A; coronin-1; coronin-1A; Coronin-like protein A; Coronin-like protein p57; FLJ41407; HCORO1; MGC117380; p57; TACOCLABP; Tryptophan aspartate-containing coat protein
Molecular Weight
Mass (kDA):
51.026 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 16p11.2 |
| Sequence: | 16; NC_000016.10 (30183410..30189076) |
Tissue Specificity
Expressed in brain, thymus, spleen, bone marrow and lymph node. Low in lung and gut.
Subcellular Localizations
Cytoplasm, cytoskeleton. Cytoplasm, cell cortex. Cytoplasmic vesicle, phagosome membrane. In non-infected macrophages, associated with the cortical microtubule network. In mycobacteria-infected macrophages, becomes progressively relocalized and retained around the mycobacterial phagosomes. Retention on the phagosomal membrane is strictly dependent on mycobacterial viability and not due to impaired acidification (By similarity).
Diseases
- Lupus Erythematosus, Systemic
- Autoimmunity
- Transfusion Associated Circulatory Overload
- Leprosy
- Immunologic Deficiency Syndromes
- Severe Combined Immunodeficiency
- Leprosy, Lepromatous
- Autoimmune Diseases
- Autoimmune Reaction
- Congenital Combined Immunodeficiency
- Cystic Fibrosis
- Malnutrition
- Communicable Diseases
Interacting Proteins
- FSD2
- GOLGA2
- STAT3
Pathways
- Localization
- Cytokine Secretion
- Virulence
- Phagocytosis
- Pathogenesis
- Secretion
- Phagosome-lysosome Fusion
- Phagosome Maturation
- Aging
- Immune Response
- Vasculogenesis
- Cell Division
- T Cell Proliferation
PTMs
- Phosphorylation
- Reduction
Research Areas
- Cell Cycle and Replication
- Immunology
- Innate Immunity
- Neuroscience
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CORO1A
bosterbio.com/bosterbio-gene-info-cards/CORO1A
References
PMID: 7758584 by Suzuki K., et al. Molecular cloning of a novel actin-binding protein, p57, with a WD repeat and a leucine zipper motif.
PMID: 10338208 by Ferrari G., et al. A coat protein on phagosomes involved in the intracellular survival of mycobacteria.