COX17 Antibodies

AND COX17 ELISA kits, COX17 Proteins

Many biological assays use antibodies to detect COX17, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with COX17 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop COX17 antibodies...

We validate the specificity of these antibodies to COX17 by testing them on tissues known to express COX17 positively and negatively. Browse below to find the COX17 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for COX17? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the COX17 IHC Guide

COX17 Infographic by Boster Bio

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Anti-COX17 Antibody Picoband®

1 Citations

IHC analysis of COX17 using anti-COX17 antibody (A04584-1)

Human, Mouse, Rat

ELISA, IF, IHC, ICC, WB

$370
Cat # A04584-1
100 μg/vial

COX17 Overview

Facts about Cytochrome c oxidase copper chaperone.

COX17 3D structure. Source: alphafold

Cytochrome c oxidase copper chaperone (COX17)

Copper metallochaperone essential for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. Binds two copper ions and delivers them into the metallochaperone SCO1 which transports the copper ions into the Cu(A) site on the cytochrome c oxidase subunit II (MT- CO2/COX2).

Gene Information

Human
Gene Name:	COX17
Uniprot:	Q14061
Entrez:	10063

Family

Belongs to:

COX17 family

Alternative Names

COX17 (yeast) homolog, cytochrome c oxidase assembly protein; COX17 cytochrome c oxidase assembly homolog (S. cerevisiae); cytochrome c oxidase assembly protein (S. cerevisiae); cytochrome c oxidase assembly protein (yeast); cytochrome c oxidase copper chaperone; human homolog of yeast mitochondrial copper recruitment; MGC104397; MGC117386

Molecular Weight

Mass (kDA):
6.915 kDA

Genomic Context


Human

Location:	3q13.33
Sequence:	3; NC_000003.12 (119669525..119677396, complement)

Tissue Specificity

Ubiquitous.

Subcellular Localizations

Mitochondrion intermembrane space. Cytoplasm.

Diseases

Cytochrome-c Oxidase Deficiency
Spindle Cell Oncocytoma Of The Adenohypophysis
Menkes Kinky Hair Syndrome
Leigh Disease
Cardiomyopathies
Hepatolenticular Degeneration
Liver Diseases
Poisoning Syndrome
Hypertrophic Cardiomyopathy
Metabolic Diseases
Hypertrophy
Sclerosis
Prion Diseases

Copper Deficiency
Primary Lateral Sclerosis
Hepatitis, Chronic
Mitochondrial Diseases
Leukoencephalopathies
Amyotrophic Lateral Sclerosis
Malignant Neoplasm Of Lung

Interacting Proteins

KATNAL1
SCO1

Pathways

Transport
Translation
Localization
Secretory Pathway
Protein Import
Excretion
Cellular Respiration
Rna Interference
Response To Stress
Gastrulation
Aerobic Respiration

Regulation Of Gene Expression
Oxidative Phosphorylation
Protein Transport
Mitochondrial Translation
Pathogenesis

PTMs

Oxidation
Phosphorylation

Reduction
Cleavage

Amidation

Research Areas

Cancer

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/COX17

References

PMID: 9050918 by Amaravadi R., et al. Isolation of a cDNA encoding the human homolog of COX17, a yeast gene essential for mitochondrial copper recruitment.

PMID: 10982038 by Punter F.A., et al. Characterization and localization of human COX17, a gene involved in mitochondrial copper transport.