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- Table of Contents
CPAMD8 Antibodies
AND CPAMD8 ELISA kits, CPAMD8 Proteins
Many biological assays use antibodies to detect CPAMD8, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CPAMD8 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CPAMD8 antibodies...
Designing an IHC experiment for CPAMD8? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the CPAMD8 IHC GuideCPAMD8 Infographic by Boster Bio
All CPAMD8 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, ICC, WB
$370
Cat # A12956-1
100 μg/vial
Cat # A12956-1
100 μg/vial
CPAMD8 Overview
Facts about C3 and PZP-like alpha-2-macroglobulin domain-containing protein 8.
C3 and PZP-like alpha-2-macroglobulin domain-containing protein 8 (CPAMD8)
Gene Information
| Human | |
|---|---|
| Gene Name: | CPAMD8 |
| Uniprot: | Q8IZJ3 |
| Entrez: | 27151 |
Family
| Belongs to: |
|---|
| protease inhibitor I39 (alpha-2-macroglobulin) family |
Alternative Names
alpha-2 macroglobulin family protein VIP; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 8; C3 and PZP-like, alpha-2-macroglobulin domain containing 8; FLJ42058; FLJ90618; K-CAP; KIAA1283; VIP
Molecular Weight
Mass (kDA):
206.702 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 19p13.11 |
| Sequence: | 19; NC_000019.10 (16892951..17026818, complement) |
Tissue Specificity
Highly expressed in the kidney, brain and testis and to a lower extent in heart, liver and small intestine (PubMed:15177561). Expressed in the lens, cornea and retina. Strongly expressed in the distal tips of the retinal neuroepithelium that form the iris and ciliary body (PubMed:27839872).
Subcellular Localizations
Secreted. Cell membrane; Peripheral membrane protein; Extracellular side.
Diseases
- Crohn Disease
Pathways
- Translation
PTMs
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CPAMD8
bosterbio.com/bosterbio-gene-info-cards/CPAMD8
References
PMID: 15177561 by Li Z.-F., et al. Identification and characterization of CPAMD8, a novel member of the complement 3/alpha2-macroglobulin family with a C-terminal Kazal domain.
PMID: 27839872 by Cheong S.S., et al. Mutations in CPAMD8 cause a unique form of autosomal-recessive anterior segment dysgenesis.