CPN1 Antibodies

AND CPN1 ELISA kits, CPN1 Proteins

Many biological assays use antibodies to detect CPN1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CPN1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CPN1 antibodies...

We validate the specificity of these antibodies to CPN1 by testing them on tissues known to express CPN1 positively and negatively. Browse below to find the CPN1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CPN1 Infographic by Boster Bio

All CPN1 Products

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Specificity

Applications

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Anti-CPN cat CPN1 Antibody

6 Q&As

Western blot analysis of lysates from RAW264

Western Blot analysis of Hela cells using CPN cat Polyclonal Antibody

Human, Mouse, Rat

ELISA, WB

$399
Cat # A05704
100μl

Anti-CPN1 Antibody Picoband®

Western blot analysis of CPN1 using anti-CPN1 antibody (A05704-2)

IF analysis of CPN1 using anti-CPN1 antibody (A05704-2)

Flow Cytometry analysis of HepG2 cells using anti-CPN1 antibody (A05704-2)

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, ICC, WB

$370
Cat # A05704-2
100 μg/vial

CPN1 (NM_001308) Human Over-expression Lysate

Human

$628
Cat # LS001369
20 µg, 100 µg

CPN1 Overview

Facts about Carboxypeptidase N catalytic chain.

CPN1 3D structure. Source: alphafold

Carboxypeptidase N catalytic chain (CPN1)

Protects the body from powerful vasoactive and inflammatory peptides comprising C-terminal Arg or Lys (such as kinins or anaphylatoxins) that are released into the circulation. .

Gene Information

Human
Gene Name:	CPN1
Uniprot:	P15169
Entrez:	1369

Family

Belongs to:

peptidase M14 family

Alternative Names

ACBP; Anaphylatoxin inactivator; Arginine carboxypeptidase; carboxypeptidase N polypeptide 1 50 kD; Carboxypeptidase N polypeptide 1; Carboxypeptidase N small subunit; carboxypeptidase N, polypeptide 1; carboxypeptidase N, polypeptide 1, 50kD; CPNcarboxypeptidase N catalytic chain; EC 3.4.17; EC 3.4.17.3; FLJ40792; kininase I; kininase-1; Lysine carboxypeptidase; Plasma carboxypeptidase B; SCPNcarboxypeptidase N catalytic subunit; Serum carboxypeptidase N

Molecular Weight

Mass (kDA):
52.286 kDA

Genomic Context


Human

Location:	10q24.2
Sequence:	10; NC_000010.11 (100042193..100081869, complement)

Tissue Specificity

Synthesized in the liver and secreted in plasma.

Subcellular Localizations

Secreted, extracellular space.

Diseases

Plant Diseases
Inflammation
Anaphylaxis
Leukoencephalopathy, Progressive Multifocal
Coughing
Inflammatory Bowel Diseases
Ulcerative Colitis
Ulcer
Coinfection
Hypertensive Disease
Encephalopathies
Dwarfism
Kidney Diseases

Allergy
Crohn Disease
Anaphylotoxin Inactivator Deficiency
Tissue Damage
Von Willebrand Disease
Colitis
Persistent Cough

Pathways

Disease Resistance
Cell Death
Defense Response
Localization
Regulation Of Cell Death
Complement Activation
Hypersensitivity
Protein Secretion
Tropism

Lipid Modification
Cell Growth
Pathogenesis
Secretion

PTMs

Cleavage

Myristoylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CPN1

References

PMID: 2912725 by Gebhard W., et al. cDNA cloning and complete primary structure of the small, active subunit of human carboxypeptidase N (kininase 1).

PMID: 3408501 by Skidgel R.A., et al. Amino acid sequence of the N-terminus and selected tryptic peptides of the active subunit of human plasma carboxypeptidase N: comparison with other carboxypeptidases.