CRTAP Antibodies

AND CRTAP ELISA kits, CRTAP Proteins

Many biological assays use antibodies to detect CRTAP, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CRTAP in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CRTAP antibodies...

We validate the specificity of these antibodies to CRTAP by testing them on tissues known to express CRTAP positively and negatively. Browse below to find the CRTAP antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for CRTAP? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the CRTAP IHC Guide

CRTAP Infographic by Boster Bio

All CRTAP Products

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Product

Figures

Specificity

Applications

Price

Anti-Cartilage-associated protein CRTAP Antibody

Western blot analysis of extracts of SW480 cells, using CRTAP antibody at 1:1000 dilution

Immunohistochemistry of paraffin-embedded rat lung using CRTAP antibody at dilution of 1:100

Immunohistochemistry of paraffin-embedded human colon using CRTAP antibody at dilution of 1:100

Human, Mouse, Rat

IHC, WB

$405
Cat # A05852
100ul

CRTAP (NM_006371) Human Over-expression Lysate

Human

$628
Cat # LS010491
20 µg, 100 µg

CRTAP (NM_006371) Human Recombinant Protein

Coomassie blue staining of purified CRTAP protein

$1249
Cat # PROTO75718
20 µg

CRTAP Overview

Facts about Cartilage-associated protein.

CRTAP 3D structure. Source: alphafold

Cartilage-associated protein (CRTAP)

Necessary for efficient 3-hydroxylation of fibrillar collagen prolyl residues. .

Gene Information

Human
Gene Name:	CRTAP
Uniprot:	O75718
Entrez:	10491

Family

Belongs to:

leprecan family

Alternative Names

cartilage associated protein; cartilage-associated protein; CASPLEPREL3; leprecan-like 3

Molecular Weight

Mass (kDA):
46.562 kDA

Genomic Context


Human

Location:	3p22.3
Sequence:	3; NC_000003.12 (33114014..33147773)

Tissue Specificity

Found in articular chondrocytes. Expressed in a variety of tissues.

Subcellular Localizations

Secreted, extracellular space, extracellular matrix.

Diseases

Osteogenesis Imperfecta
Fracture
Connective Tissue Diseases
Osteoporosis
Hereditary Diseases
Dentinogenesis Imperfecta
Bone Diseases
Mucopolysaccharidosis Iv
Dysplasia
Dwarfism
Metabolic Bone Disorder
Scleral Diseases

Scoliosis, Unspecified
Multiple Fractures
Blue Sclera
Embryonic Mosaic
Bone Diseases, Developmental
Collagen Diseases
Burkitt Lymphoma

Pathways

Pathogenesis
Dentinogenesis
Bone Development
Secretion
Fibril Organization
Glycosylation
Methylation
Translation
Collagen Fibril Organization

Bone Remodeling
Bone Resorption
Viral Replication
Bone Mineralization

PTMs

Hydroxylation

Reduction

Glycosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CRTAP

References

PMID: 10702664 by Tonachini L., et al. cDNA cloning, characterization and chromosome mapping of the gene encoding human cartilage associated protein (CRTAP).

PMID: 17055431 by Morello R., et al. CRTAP is required for prolyl 3-hydroxylation and mutations cause recessive osteogenesis imperfecta.