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- Table of Contents
Cystatin-A Antibodies
AND CSTA ELISA kits, Cystatin-A Proteins
Many biological assays use antibodies to detect Cystatin-A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Cystatin-A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Cystatin-A antibodies...
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CSTA Infographic by Boster Bio
All CSTA Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
IF, ICC, WB
$370
Cat # PB9564
100 μg/vial
Cat # PB9564
100 μg/vial
Human
ELISA
$480
Cat # EKC1548
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1548
1 kit, containing one 96-well plate and all necessary reagents
Human, Mouse, Rat
Flow Cytometry, WB
$370
Cat # M03914
100 μl/vial
Cat # M03914
100 μl/vial
CSTA Overview
Facts about Cystatin-A.
Cystatin-A (CSTA)
This is an intracellular thiol proteinase inhibitor. Has an important part in desmosome-mediated cell-cell adhesion in the lower levels of the skin.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | CSTA |
| Uniprot: | P01040 |
| Entrez: | 1475 |
Family
| Belongs to: |
|---|
| cystatin family |
Alternative Names
AREI; CSTA; cystatin A (stefin A); Cystatin A; cystatin AS; cystatin-A; Stefin A; STF1; STF1Cystatin-AS; STFA; STFAStefin-A
Molecular Weight
Mass (kDA):
11.006 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 3q21.1 |
| Sequence: | 3; NC_000003.12 (122325248..122341969) |
Tissue Specificity
Expressed in the skin throughout the epidermis.
Subcellular Localizations
Cytoplasm.
Diseases
- Neoplasms
- Malignant Neoplasms
- Carcinoma
- Malignant Paraganglionic Neoplasm
- Malignant Squamous Cell Neoplasm
- Neoplasm Metastasis
- Malignant Neoplasm Of Breast
- Tumor Progression
- Neoplasm Invasiveness
- Head And Neck Carcinoma
- Tissue Adhesions
- Mammary Neoplasms
- Adenocarcinoma
Pathways
- Pathogenesis
- Secretion
- Proteolysis
- Cell Proliferation
- Localization
- Cell Adhesion
- Immune Response
- Reverse Transcription
- Translation
- Cell Differentiation
- Transport
- Cell Migration
- Mrna Destabilization
PTMs
- Phosphorylation
- Cleavage
Research Areas
- Cancer
- Tumor Suppressors
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CSTA
bosterbio.com/bosterbio-gene-info-cards/CSTA
References
PMID: 6689312 by Machleidt W., et al. Protein inhibitors of cysteine proteinases. II. Primary structure of stefin, a cytosolic protein inhibitor of cysteine proteinases from human polymorphonuclear granulocytes.
PMID: 2768224 by Takeda A., et al. Comparative studies on the primary structure of human cystatin as from epidermis, liver, spleen, and leukocytes.