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- Table of Contents
Cystatin-A Antibodies
AND CSTA ELISA kits, Cystatin-A Proteins
Many biological assays use antibodies to detect Cystatin-A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Cystatin-A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Cystatin-A antibodies...
Designing a Western blot for Cystatin-A? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the CSTA Western Blot GuideCSTA Infographic by Boster Bio
All CSTA Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, WB
$370
Cat # M03914
100 μl/vial
Cat # M03914
100 μl/vial
Human
ELISA
$480
Cat # EKC1548
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1548
1 kit, containing one 96-well plate and all necessary reagents
CSTA Overview
Facts about Cystatin-A.
Cystatin-A (CSTA)
This is an intracellular thiol proteinase inhibitor. Has an important part in desmosome-mediated cell-cell adhesion in the lower levels of the skin.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | CSTA |
| Uniprot: | P01040 |
| Entrez: | 1475 |
Family
| Belongs to: |
|---|
| cystatin family |
Alternative Names
AREI; CSTA; cystatin A (stefin A); Cystatin A; cystatin AS; cystatin-A; Stefin A; STF1; STF1Cystatin-AS; STFA; STFAStefin-A
Molecular Weight
Mass (kDA):
11.006 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 3q21.1 |
| Sequence: | 3; NC_000003.12 (122325248..122341969) |
Tissue Specificity
Expressed in the skin throughout the epidermis.
Subcellular Localizations
Cytoplasm.
Diseases
- Neoplasms
- Malignant Neoplasms
- Carcinoma
- Malignant Paraganglionic Neoplasm
- Malignant Squamous Cell Neoplasm
- Neoplasm Metastasis
- Malignant Neoplasm Of Breast
- Tumor Progression
- Neoplasm Invasiveness
- Head And Neck Carcinoma
- Tissue Adhesions
- Mammary Neoplasms
- Adenocarcinoma
Pathways
- Pathogenesis
- Secretion
- Proteolysis
- Cell Proliferation
- Localization
- Cell Adhesion
- Immune Response
- Reverse Transcription
- Translation
- Cell Differentiation
- Transport
- Cell Migration
- Mrna Destabilization
PTMs
- Phosphorylation
- Cleavage
Research Areas
- Cancer
- Tumor Suppressors
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CSTA
bosterbio.com/bosterbio-gene-info-cards/CSTA
References
PMID: 6689312 by Machleidt W., et al. Protein inhibitors of cysteine proteinases. II. Primary structure of stefin, a cytosolic protein inhibitor of cysteine proteinases from human polymorphonuclear granulocytes.
PMID: 2768224 by Takeda A., et al. Comparative studies on the primary structure of human cystatin as from epidermis, liver, spleen, and leukocytes.