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In contrast, it's not involved in steady state translation, that takes place when the CBC complex is replaced by cytoplasmic cap-binding protein eIF4E. Also required for nonsense-mediated mRNA decay (NMD), the pioneer round of mRNA translation mediated by the cap-binding complicated playing a central role in nonsense-mediated mRNA decay (NMD).
|Sequence:||18; NC_000018.10 (48539031..48863217)|
Cytoplasm, perinuclear region.