Chymotrypsin-C Antibodies

AND CTRC ELISA kits, Chymotrypsin-C Proteins

Many biological assays use antibodies to detect Chymotrypsin-C, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Chymotrypsin-C in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Chymotrypsin-C antibodies...

We validate the specificity of these antibodies to Chymotrypsin-C by testing them on tissues known to express CTRC positively and negatively. Browse below to find the CTRC antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for Chymotrypsin-C? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the CTRC IHC Guide

CTRC Infographic by Boster Bio

All CTRC Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Human CTRC/Chymotrypsin-C ELISA Kit PicoKine®

Human

ELISA

$750
Cat # EK2001
96 wells/kit, with removable strips.

Anti-CTRC Antibody Picoband®

Western blot analysis of CTRC using anti-CTRC antibody (A03540-1)

IHC analysis of CTRC using anti-CTRC antibody (A03540-1)

Human, Rat

IHC, WB

$370
Cat # A03540-1
100 μg/vial

Chymotrypsin (CTRC) (NM_007272) Human Over-expression Lysate

Human

$628
Cat # LS011330
20 µg, 100 µg

Human EphA2 Recombinant Protein

1 Citations

3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain

SDS-PAGE, Bioactivity

$248
Cat # PROTP29317
Starting from 10ug

CTRC Overview

Facts about Chymotrypsin-C.

CTRC 3D structure. Source: alphafold

Chymotrypsin-C (CTRC)

Regulates activation and degradation of trypsinogens and procarboxypeptidases by targeting specific cleavage sites in their zymogen precursors. Has chymotrypsin-type protease activity and hypocalcemic action.

Gene Information

Human
Gene Name:	CTRC
Uniprot:	Q99895
Entrez:	11330

Family

Belongs to:

peptidase S1 family

Alternative Names

Caldecrin; chymotrypsin C (caldecrin); Chymotrypsin C; chymotrypsin-C; CLCR; CLCRserum calcium decreasing factor; CTRC; EC 3.4.21; EC 3.4.21.2; ELA4; elastase 4; Elastase IV

Molecular Weight

Mass (kDA):
29.484 kDA

Genomic Context


Human

Location:	1p36.21
Sequence:	1; NC_000001.11 (15438442..15449247)

Tissue Specificity

Pancreas.

Diseases

Pancreatitis
Pancreatitis, Chronic
Fibrosis
Cystic Fibrosis
Pain
Appendicitis
Malignant Neoplasms
Inflammation
Abdominal Pain
Inflammatory Disorder
Adolescent Idiopathic Scoliosis

Acquired Kyphosis
Endoplasmic Reticulum Stress
Neoplasms
Scoliosis, Unspecified
Diabetes Mellitus
Pancreatitis, Alcoholic

Interacting Proteins

KRTAP10-7

Pathways

Pathogenesis
Secretion
Trypsinogen Activation
Transport
Intracellular Transport
Zymogen Activation
Glycosylation

Amelogenesis
Response To Food

PTMs

Cleavage

Glycosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CTRC

References

PMID: 8635596 by Tomomura A., et al. Molecular cloning and expression of human caldecrin.

PMID: 9538241 by Yoshino-Yasuda I., et al. Caldecrin is a novel-type serine protease expressed in pancreas, but its homologue, elastase IV, is an artifact during cloning derived from caldecrin gene.