CX3C chemokine receptor 1 Antibodies

AND CX3CR1 ELISA kits, CX3C chemokine receptor 1 Proteins

Many biological assays use antibodies to detect CX3C chemokine receptor 1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CX3C chemokine receptor 1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CX3C chemokine receptor 1 antibodies...

We validate the specificity of these antibodies to CX3C chemokine receptor 1 by testing them on tissues known to express CX3CR1 positively and negatively. Browse below to find the CX3CR1 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for CX3C chemokine receptor 1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the CX3CR1 IHC Guide

CX3CR1 Infographic by Boster Bio

All CX3CR1 Products

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Anti-CX3CR1 Antibody

Human

ELISA, Flow Cytometry, IHC

$370
Cat # A00280-2
100 μg/vial

CX3CR1 Overview

Facts about CX3C chemokine receptor 1.

CX3CR1 3D structure. Source: alphafold

CX3C chemokine receptor 1 (CX3CR1)

Receptor for the CX3C chemokine fractalkine (CX3CL1); binds to CX3CL1 and mediates both its adhesive and migratory functions (PubMed:9390561, PubMed:23125415). Acts as coreceptor with CD4 for HIV-1 virus envelope protein (in vitro) (PubMed:9726990).

Isoform 2 and isoform 3 seem to be more potent HIV-1 coreceptors compared to isoform 1 (PubMed:14607932). .

Gene Information

Human
Gene Name:	CX3CR1
Uniprot:	P49238
Entrez:	1524

Family

Belongs to:

G-protein coupled receptor 1 family

Alternative Names

Beta chemokine receptor-like 1; CCRL1; chemokine (C-C) receptor-like 1; chemokine (C-X3-C motif) receptor 1; chemokine (C-X3-C) receptor 1; CMKbRL1; CMK-BRL1; CMK-BRL-1; CMKDR1; CX3C chemokine receptor 1; CX3CR1; Fractalkine receptor; G protein-coupled receptor 13; GPR13G-protein coupled receptor 13; GPRV28; V28; V28C-X3-C CKR-1

Molecular Weight

Mass (kDA):
40.396 kDA

Genomic Context


Human

Location:	3p22.2
Sequence:	3; NC_000003.12 (39263494..39281735, complement)

Tissue Specificity

Expressed in lymphoid and neural tissues.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

Diseases

Inflammation
Tissue Adhesions
Atherosclerosis
Neoplasms
Hiv Infections
Nervousness
Malignant Neoplasms
Age Related Macular Degeneration
Pain
Coronary Artery Disease
Arthritis
Inflammatory Response

Autoimmune Reaction
Immunologic Deficiency Syndromes
Rheumatoid Arthritis
Dental Plaque
Neoplasm Metastasis
Cholangiocarcinoma
Acquired Immunodeficiency Syndrome

Pathways

Pathogenesis
Chemotaxis
Immune Response
Cell Adhesion
Inflammatory Response
Secretion
Angiogenesis
Localization
Cell Migration
Phagocytosis
Leukocyte Migration
Cell Death
Neuroprotection

Cell Activation
Innate Immune Response
Cytokine Production
Cell Proliferation
Cell Differentiation
Cell-cell Adhesion
Tropism

PTMs

Phosphorylation
Cleavage

Glycosylation
Acetylation

Methylation

Research Areas

Chemokines and Cytokines
GPCR

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CX3CR1

References

PMID: 7590284 by Raport C.J., et al. The orphan G-protein-coupled receptor-encoding gene V28 is closely related to genes for chemokine receptors and is expressed in lymphoid and neural tissues.

PMID: 7646814 by Combadiere C., et al. Cloning, chromosomal localization, and RNA expression of a human beta chemokine receptor-like gene.