CYB5R3 Antibodies

AND CYB5R3 ELISA kits, CYB5R3 Proteins

Many biological assays use antibodies to detect CYB5R3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CYB5R3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CYB5R3 antibodies...

We validate the specificity of these antibodies to CYB5R3 by testing them on tissues known to express CYB5R3 positively and negatively. Browse below to find the CYB5R3 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for CYB5R3? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the CYB5R3 Western Blot Guide

CYB5R3 Infographic by Boster Bio

All CYB5R3 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-CYB5R3 Antibody Picoband®

Western blot analysis of CYB5R3 using anti-CYB5R3 antibody (A03487-4)

IF analysis of CYB5R3 using anti-CYB5R3 antibody (A03487-4)

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, ICC, WB

$370
Cat # A03487-4
100 μg/vial

Anti-CYB5R3 Rabbit Monoclonal Antibody

Western blot analysis of CYB5R3 expression in A431 cell lysate

Human, Rat

IHC, WB

$370
Cat # M03487-2
100 μl/vial

CYB5R3 (NM_000398) Human Over-expression Lysate

CYB5R3 Human Over-expression Lysates NM_000398

Human

$628
Cat # LS001727
20 µg, 100 µg

CYB5R3 (NM_000398) Human Recombinant Protein

Coomassie blue staining of purified CYB5R3 protein

$1062
Cat # PROTP00387
20 µg

CYB5R3 Overview

Facts about NADH-cytochrome b5 reductase 3.

CYB5R3 3D structure. Source: alphafold

NADH-cytochrome b5 reductase 3 (CYB5R3)

Desaturation and elongation of fatty acids, cholesterol biosynthesis, drug metabolism, and, in erythrocyte, methemoglobin reduction. .

Gene Information

Human
Gene Name:	CYB5R3
Uniprot:	P00387
Entrez:	1727

Family

Belongs to:

flavoprotein pyridine nucleotide cytochrome reductase family

Alternative Names

B5RNADH-cytochrome b5 reductase 3; cytochrome b5 reductase 3; Cytochrome b5 reductase; DIA1NADH-cytochrome b5 reductase 3 membrane-bound form; diaphorase (NADH) (cytochrome b-5 reductase); diaphorase-1; EC 1.6.2.2; NADH-cytochrome b5 reductase 3 soluble form

Molecular Weight

Mass (kDA):
34.235 kDA

Genomic Context


Human

Location:	22q13.2
Sequence:	22; NC_000022.11 (42617840..42649392, complement)

Tissue Specificity

Isoform 2 is expressed at late stages of erythroid maturation.

Subcellular Localizations

[Isoform 1]: Endoplasmic reticulum membrane; Lipid-anchor; Cytoplasmic side. Mitochondrion outer membrane; Lipid-anchor; Cytoplasmic side.; [Isoform 2]: Cytoplasm. Produces the soluble form found in erythrocytes.

Diseases

Methemoglobinemia
Congenital Methemoglobinemia
Cyanosis
Adenoma
Familial Methemoglobinemia
Lung Diseases
Lung Diseases, Obstructive
Chronic Obstructive Airway Disease
Heterodisomy, Uniparental
Delayed Hypersensitivity
Exanthema

Congenital Heart Disease
Dyskinetic Syndrome
Malignant Neoplasms
Neoplasms
Mammary Neoplasms

Interacting Proteins

HBA1

Pathways

Hypersensitivity
Senescence
Cell Adhesion
System Development
Cell Cycle
Aging
Immune Response

Glycolysis

PTMs

Phosphorylation

Oxidation

Research Areas

Cancer
Lipid and Metabolism

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CYB5R3

References

PMID: 2479590 by Tomatsu S., et al. The organization and the complete nucleotide sequence of the human NADH-cytochrome b5 reductase gene.

PMID: 3035541 by Yubisui T., et al. Molecular cloning of cDNAs of human liver and placenta NADH- cytochrome b5 reductase.