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CYP51A1 Antibodies
AND CYP51A1 ELISA kits, CYP51A1 Proteins
Many biological assays use antibodies to detect CYP51A1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CYP51A1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CYP51A1 antibodies...
Designing a Western blot for CYP51A1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the CYP51A1 Western Blot GuideCYP51A1 Infographic by Boster Bio
All CYP51A1 Products
Product
Figures
Specificity
Applications
Price
Human, Monkey, Mouse
ELISA, Flow Cytometry, IF, ICC, WB
$370
Cat # A04032-1
100 μg/vial
Cat # A04032-1
100 μg/vial
CYP51A1 Overview
Facts about Lanosterol 14-alpha demethylase.
Lanosterol 14-alpha demethylase (CYP51A1)
Catalyzes C14-demethylation of lanosterol; it transforms lanosterol to 4,4'-dimethyl cholesta-8,14,24-triene-3-beta-ol. .
Gene Information
| Human | |
|---|---|
| Gene Name: | CYP51A1 |
| Uniprot: | Q16850 |
| Entrez: | 1595 |
Family
| Belongs to: |
|---|
| cytochrome P450 family |
Alternative Names
CP51; CYP51Cytochrome P450LI; CYPL1; CYPLI; Cytochrome P450 51A1; cytochrome P450, family 51, subfamily A, polypeptide 1; Cytochrome P450-14DM; EC 1.14.13.70; lanosterol 14-alpha demethylase; lanosterol 14-alpha-demethylase; LDMCytochrome P45014DM; P450-14DM; P450L1,51 (lanosterol 14-alpha-demethylase); Sterol 14-alpha demethylase
Molecular Weight
Mass (kDA):
56.806 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 7q21.2 |
| Sequence: | 7; NC_000007.14 (92112149..92134745, complement) |
Tissue Specificity
Ubiquitously expressed with highest levels in testis, ovary, adrenal, prostate, liver, kidney and lung.
Subcellular Localizations
Endoplasmic reticulum membrane; Single-pass membrane protein. Microsome membrane; Single-pass membrane protein.
Diseases
- Tuberculosis
- Candidiasis
- Infective Disorder
- Mycoses
- Acquired Immunodeficiency Syndrome
- Infection By Cryptococcus Neoformans
- Malignant Neoplasms
- Neoplasms
- Liver Carcinoma
- Chagas Disease
- Aids-related Opportunistic Infections
- Opportunistic Infections
- Oropharyngeal Disorders
Pathways
- Meiosis
- Cell Cycle
- Transport
- Spermatogenesis
- Demethylation
- Cell Proliferation
- Oocyte Maturation
- Cell Growth
- Fertilization
- Translation
- G1 Phase
- Ovulation
- Localization
PTMs
- Demethylation
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CYP51A1
bosterbio.com/bosterbio-gene-info-cards/CYP51A1
References
PMID: 8619637 by Stroemstedt M., et al. The ubiquitously expressed human CYP51 encodes lanosterol 14 alpha- demethylase, a cytochrome P450 whose expression is regulated by oxysterols.
PMID: 8797093 by Aoyama Y., et al. Sterol 14-demethylase P450 (P45014DM*) is one of the most ancient and conserved P450 species.