CARF Antibodies

AND CARF ELISA kits, CARF Proteins

Many biological assays use antibodies to detect CARF, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CARF in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CARF antibodies...

We validate the specificity of these antibodies to CARF by testing them on tissues known to express CARF positively and negatively. Browse below to find the CARF antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for CARF? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the CARF IHC Guide

CARF Infographic by Boster Bio

All CARF Products

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Product

Figures

Specificity

Applications

Price

Anti-CDKN2AIP/CARF Antibody Picoband®

Western blot analysis of CDKN2AIP/CARF using anti-CDKN2AIP/CARF antibody (A05786-1)

Flow Cytometry analysis of NIH/3T3 cells using anti-CDKN2AIP/CARF antibody (A05786-1)

Mouse, Rat

ELISA, Flow Cytometry, WB

$370
Cat # A05786-1
100 μg/vial

Anti-ALS2CR8 Antibody

Western Blot analysis of various cells using ALS2CR8 Polyclonal Antibody

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using ALS2CR8 Antibody

Western blot analysis of lysates from HUVEC cells, using ALS2CR8 Antibody

Human, Mouse, Rat

ELISA, IF, IHC, ICC, WB

$335
Cat # A30570
100ul

CARF Overview

Facts about Calcium-responsive transcription factor.

CARF 3D structure. Source: alphafold

Calcium-responsive transcription factor (CARF)

Acts as a transcriptional activator that mediates the calcium- and neuron-selective induction of BDNF exon III transcription. Binds to the consensus calcium-response element CaRE1 5'-CTATTTCGAG-3' sequence.

Gene Information

Human
Gene Name:	CARF
Uniprot:	Q8N187
Entrez:	79800

Family

Belongs to:

No superfamily

Alternative Names

amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 8; amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein; Calcium-response factor; CaRF; CARFDKFZp667N246; FLJ12675; FLJ21579; NYD-SP24; Testis development protein NYD-SP24

Molecular Weight

Mass (kDA):
80.698 kDA

Genomic Context


Human

Location:	2q33.2
Sequence:	2; NC_000002.12 (202912218..202988263)

Subcellular Localizations

Nucleus.

Diseases

Neoplasms
Malignant Neoplasms
Carcinogenesis
Adenocarcinoma
Solid Tumor
Pancreatic Neoplasm
Malignant Neoplasm Of Breast
Ductal Carcinoma

Esophageal Neoplasms
Esophageal Adenocarcinoma

Pathways

Senescence
Cell Cycle
Replicative Senescence
Pathogenesis

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CARF

References

PMID: 11586298 by Hadano S., et al. A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2.

PMID: 11832226 by Tao X., et al. A calcium-responsive transcription factor, CaRF, that regulates neuronal activity-dependent expression of BDNF.