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- Table of Contents
CD38 Antibodies
AND CD38 ELISA kits, CD38 Proteins
Many biological assays use antibodies to detect CD38, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CD38 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CD38 antibodies...
Designing a Western blot for CD38? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the CD38 Western Blot GuideCD38 Infographic by Boster Bio
All CD38 Products
Product
Figures
Specificity
Applications
Price
Human
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A00193-3
100 μg/vial
Cat # A00193-3
100 μg/vial
Human
ELISA, IP, IF, IHC, WB
$146
Cat # M00193-7
20μL, 40μL, 100μL, 200μL
Cat # M00193-7
20μL, 40μL, 100μL, 200μL
Human, Mouse, Rat
ELISA, IP, IF, IHC, WB
$146
Cat # M00193-8
20μL, 40μL, 100μL, 200μL
Cat # M00193-8
20μL, 40μL, 100μL, 200μL
Human, Mouse
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00193-5
100 μg
Cat # M00193-5
100 μg
Human, Mouse
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00193-4
100 μg
Cat # M00193-4
100 μg
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00193-3
100 μg
Cat # M00193-3
100 μg
Human
Flow Cytometry, IHC-P, IHC-F, WB
$301
Cat # M00193-1
0.1 mg
Cat # M00193-1
0.1 mg
Human, Mouse
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00193-6
100 μg
Cat # M00193-6
100 μg
CD38 Overview
Facts about ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1.
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 (CD38)
Synthesizes the next messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity.
Additionally moonlights as a receptor in cells of the immune system. .
Gene Information
| Human | |
|---|---|
| Gene Name: | CD38 |
| Uniprot: | P28907 |
| Entrez: | 952 |
Family
| Belongs to: |
|---|
| ADP-ribosyl cyclase family |
Alternative Names
ADP-ribosyl cyclase 1; ADP-ribosyl Cyclase; ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase; cADPr hydrolase 1; CD38 antigen (p45); CD38 antigen; CD38 molecule; CD38; Cyclic ADP-ribose hydrolase 1; Cyclic ADP-ribose Hydrolase; EC 3.2.2.5; NAD(+) nucleosidase; T10
Molecular Weight
Mass (kDA):
34.328 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 4p15.32 |
| Sequence: | 4; NC_000004.12 (15778328..15853232) |
Tissue Specificity
Expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma.
Subcellular Localizations
Membrane; Single-pass type II membrane protein.
Diseases
- Leukemia
- Chronic Lymphocytic Leukemia
- Lymphoid Leukemia
- Hiv Infections
- Neoplasms
- Immunologic Deficiency Syndromes
- Multiple Myeloma
- Lymphoma
- Malignant Neoplasms
- Myeloid Leukemia
- Tissue Adhesions
- Malignant Paraganglionic Neoplasm
Pathways
- Secretion
- Cell Activation
- Pathogenesis
- Cell Cycle
- Cell Proliferation
- Cell Differentiation
- T Cell Activation
- Immune Response
- Cell Death
- Cell Growth
- Cell Adhesion
- Localization
- Insulin Secretion
PTMs
- Phosphorylation
- Cleavage
- Glycosylation
- Ribosylation
- Methylation
- Acetylation
- Biotinylation
- Dephosphorylation
Research Areas
- Apoptosis
- Cell Biology
- Hematopoietic Stem Cell Markers
- Immunology
- Stem Cell Markers
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CD38
bosterbio.com/bosterbio-gene-info-cards/CD38
References
PMID: 2319135 by Jackson D.G., et al. Isolation of a cDNA encoding the human CD38 (T10) molecule, a cell surface glycoprotein with an unusual discontinuous pattern of expression during lymphocyte differentiation.
PMID: 9074508 by Nata K., et al. Human gene encoding CD38 (ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase): organization, nucleotide sequence and alternative splicing.