Sororin Antibodies

AND Cdca5 ELISA kits, Sororin Proteins

Many biological assays use antibodies to detect Sororin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Sororin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Sororin antibodies...

We validate the specificity of these antibodies to Sororin by testing them on tissues known to express Cdca5 positively and negatively. Browse below to find the Cdca5 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for Sororin? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the CDCA5 IHC Guide

Cdca5 Infographic by Boster Bio

All Cdca5 Products

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Specificity

Applications

Price

Anti-CDCA5/Sororin Rabbit Monoclonal Antibody

Immunohistochemical analysis of paraffin-embedded human colon, using CDCA5 Antibody

Immunofluorescent analysis of Hela cells, using CDCA5 Antibody

Western blot analysis of CDCA5 using anti-CDCA5 antibody (M05043)

Human

Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # M05043
100 μl

CDCA5 (NM_080668) Human Over-expression Lysate

Human

$628
Cat # LS113130
20 µg, 100 µg

Cdca5 Overview

Facts about Sororin.

Sororin (Cdca5)

Regulator of sister chromatid cohesion in mitosis stabilizing cohesin complex association with chromatin. May antagonize the action of WAPL which arouses cohesin dissociation from chromatin.

Cohesion makes sure that chromosome partitioning is true in both meiotic and mitotic cells and plays an important role in DNA repair. Required for efficient DNA double-stranded break repair.

Gene Information

Mouse
Gene Name:	Cdca5
Uniprot:	Q9CPY3
Entrez:	67849

Family

Belongs to:

sororin family

Alternative Names

cell division cycle associated 5; Cell division cycle-associated protein 5; MGC16386; p35; SORORIN

Molecular Weight

Mass (kDA):
28.991 kDA

Genomic Context


Mouse

Location:	19\|19 A
Sequence:	19;

Diseases

Malignant Neoplasms
Neoplasms
Neoplasm Metastasis
Malignant Paraganglionic Neoplasm
Pancreatic Neoplasm
Cell Invasion
Lung Neoplasms
Alzheimer's Disease
Carcinoma
Dysplasia
Adenocarcinoma
Non-small Cell Lung Carcinoma

Hepatitis
Diabetes Mellitus
Cornelia De Lange Syndrome
Malignant Neoplasm Of Lung
Carcinoma, Pancreatic Ductal
Malignant Neoplasm Of Pancreas
Malignant Neoplasm Of Prostate

Pathways

Sister Chromatid Cohesion
Anaphase
Mitosis
Cell Cycle
Prophase
Interphase
Localization
Dna Replication
Cell Proliferation
Metaphase
Drug Resistance
S Phase
Hyperphosphorylation

Cellular Senescence
Brain Development
Nuclear Export
Response To Oxidative Stress
Cell Division
Cell Motility
Response To Hydrogen Peroxide

PTMs

Phosphorylation
Cleavage

Ubiquitination
Deacetylation

Acetylation

Research Areas

Cell Cycle and Replication
Core ESC-Like Genes
Stem Cell Markers

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Cdca5

References

PMID: 21111234 by Nishiyama T., et al. Sororin mediates sister chromatid cohesion by antagonizing wapl.