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- Table of Contents
Chromogranin-A Antibodies
AND CHGA ELISA kits, Chromogranin-A Proteins
Many biological assays use antibodies to detect Chromogranin-A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Chromogranin-A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Chromogranin-A antibodies...
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CHGA Infographic by Boster Bio
All CHGA Products
Product
Figures
Specificity
Applications
Price
Human
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M01256-1
100 μl
Cat # M01256-1
100 μl
Anti-Chromogranin A/Chga Antibody Picoband®
1 Citations
Mouse, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A01256-2
100 μg/vial
Cat # A01256-2
100 μg/vial
Human, Mouse
IF, IHC, WB
$523
Cat # M01256-2
100 µl
Cat # M01256-2
100 µl
Human
$628
Cat # LS001113
20 µg, 100 µg
Cat # LS001113
20 µg, 100 µg
Human
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A01256-4
100 µg/vial
Cat # A01256-4
100 µg/vial
Human, Mouse, Rat
ELISA, IP, IF, IHC, WB
$146
Cat # M01256-3
20μL, 40μL, 100μL, 200μL
Cat # M01256-3
20μL, 40μL, 100μL, 200μL
Human, Mouse, Rat
IF, IHC, ICC, WB
$370
Cat # M01256-4
100 μl/vial
Cat # M01256-4
100 μl/vial
CHGA Overview
Facts about Chromogranin-A.
Chromogranin-A (CHGA)
Pancreastatin: Strongly inhibits glucose induced insulin release from the pancreas. .
Gene Information
| Human | |
|---|---|
| Gene Name: | CHGA |
| Uniprot: | P10645 |
| Entrez: | 1113 |
Family
| Belongs to: |
|---|
| chromogranin/secretogranin protein family |
Alternative Names
betagranin (N-terminal fragment of chromogranin A); Betagranin; Catestatin; CGA; CHGA; Chromofungin; chromogranin A (parathyroid secretory protein 1); Chromogranin A; chromogranin-A; Pancreastatin; Parastatin; Parathyroid Secretory Protein 1; Pituitary Secretory Protein I; SP-I
Molecular Weight
Mass (kDA):
50.688 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 14q32.12 |
| Sequence: | 14; NC_000014.9 (92922594..92935293) |
Tissue Specificity
GE-25 is found in the brain.
Subcellular Localizations
[Serpinin]: Secreted. Cytoplasmic vesicle, secretory vesicle. Pyroglutaminated serpinin localizes to secretory vesicle.; Cytoplasmic vesicle, secretory vesicle. Cytoplasmic vesicle, secretory vesicle, neuronal dense core vesicle. Secreted. Associated with the secretory granule membrane through direct interaction to SCG3 that in turn binds to cholesterol-enriched lipid rafts in intragranular conditions. In pituitary gonadotropes, located in large secretory granules.
Diseases
- Neoplasms
- Carcinoma
- Neuroendocrine Tumors
- Malignant Neoplasms
- Pheochromocytoma
- Carcinoid Tumor
- Hypertensive Disease
- Prostatic Neoplasms
- Malignant Neoplasm Of Prostate
- Pituitary Diseases
- Neoplasm Metastasis
- Lung Neoplasms
- Adenocarcinoma
Pathways
- Secretion
- Localization
- Exocytosis
- Catecholamine Secretion
- Pathogenesis
- Secretory Pathway
- Hormone Secretion
- Regulated Secretory Pathway
- Cell Proliferation
- Proteolysis
- Glomerular Filtration
- Cell Differentiation
- Excretion
PTMs
- Cleavage
- Phosphorylation
- Glycosylation
- Amidation
- Methylation
Research Areas
- Cancer
- Neuronal Cell Markers
- Tumor Biomarkers
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CHGA
bosterbio.com/bosterbio-gene-info-cards/CHGA
References
PMID: 2445752 by Konecki D.S., et al. The primary structure of human chromogranin A and pancreastatin.
PMID: 3403545 by Helman L.J., et al. Molecular cloning and primary structure of human chromogranin A (secretory protein I) cDNA.
1 Publications of Boster Chromogranin-A Antibodies & ELISA Kits
- PubMed ID: 31732520, Glumac PM,Gallant JP,Shapovalova M,Li Y,Murugan P,Gupta S,Coleman IM,Nelson PS,D...
*More publications can be found for each product on its corresponding product page