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- Table of Contents
Designing a Western blot for Cop1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the COP1 Western Blot GuideFacts about E3 ubiquitin-protein ligase COP1.
Directly involved in p53 (TP53) ubiquitination and degradation, thereby abolishing p53-dependent transcription and apoptosis. Ubiquitinates p53 independently of MDM2 or RCHY1.
| Mouse | |
|---|---|
| Gene Name: | Cop1 |
| Uniprot: | Q9R1A8 |
| Entrez: | 26374 |

| Belongs to: |
|---|
| COP1 family |

E3 ubiquitin-protein ligase COP1
Mass (kDA):
80.441 kDA

| Mouse | |
|---|---|
| Location: | 1|1 H1 |
| Sequence: | 1; |

PMID: 10395541 by Wang H., et al. Evidence for functional conservation of a mammalian homologue of the light-responsive plant protein COP1.