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- Table of Contents
CXCR5 Antibodies
AND CXCR5 ELISA kits, CXCR5 Proteins
Many biological assays use antibodies to detect CXCR5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CXCR5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CXCR5 antibodies...
Designing a Western blot for CXCR5? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the CXCR5 Western Blot GuideDesigning an IHC experiment for CXCR5? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the CXCR5 IHC GuideCXCR5 Infographic by Boster Bio
All CXCR5 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M00663-1
100 μl/vial
Cat # M00663-1
100 μl/vial
Anti-CXCR5 Antibody Picoband®
1 Citations
Human, Mouse, Rat
ELISA, Flow Cytometry, WB
$370
Cat # A00663-2
100 μg/vial
Cat # A00663-2
100 μg/vial
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00663-2
100 μg
Cat # M00663-2
100 μg
CXCR5 Overview
Facts about C-X-C chemokine receptor type 5.
C-X-C chemokine receptor type 5 (CXCR5)
Cytokine receptor which binds to B-lymphocyte chemoattractant (BLC). Involved in B-cell migration to B-cell follicles of spleen and Peyer patches but not to those of mesenteric or peripheral lymph nodes.
May have a regulatory function in Burkitt lymphoma (BL) lymphomagenesis or B-cell differentiation. .
Gene Information
| Human | |
|---|---|
| Gene Name: | CXCR5 |
| Uniprot: | P32302 |
| Entrez: | 643 |
Family
| Belongs to: |
|---|
| G-protein coupled receptor 1 family |
Alternative Names
BLR1; BLR1MDR-15; Burkitt lymphoma receptor 1; Burkitt lymphoma receptor 1, GTP binding protein (chemokine (C-X-C motif)receptor 5); Burkitt lymphoma receptor 1, GTP-binding protein; CD185 antigen; CD185; chemokine (C-X-C motif) receptor 5; C-X-C chemokine receptor type 5; CXCR5; CXC-R5; MDR15CXCR-5; MGC117347; Monocyte-derived receptor 15
Molecular Weight
Mass (kDA):
41.955 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 11q23.3 |
| Sequence: | 11; NC_000011.10 (118883892..118897787) |
Tissue Specificity
Expression in mature B-cells and Burkitt lymphoma cells.
Subcellular Localizations
Cell membrane; Multi-pass membrane protein.
Diseases
- Lymphoma
- Inflammation
- Neoplasms
- Autoimmune Reaction
- Autoimmune Diseases
- Tissue Adhesions
- Malignant Neoplasms
- Leukemia
- Neoplasm Metastasis
- Arthritis
- Malignant Paraganglionic Neoplasm
- Rheumatoid Arthritis
- B-cell Lymphomas
Interacting Proteins
- CXCR4
- GNA13
- GNAI2
- GNB3
- GNG8
Pathways
- Chemotaxis
- Pathogenesis
- Cell Differentiation
- Immune Response
- Localization
- Cell Migration
- Cell Proliferation
- Cell Development
- Cell Activation
- Secretion
- Germinal Center Formation
- Cell Cycle
- B Cell Differentiation
PTMs
- Phosphorylation
- Cleavage
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CXCR5
bosterbio.com/bosterbio-gene-info-cards/CXCR5
References
PMID: 1425907 by Dobner T., et al. Differentiation-specific expression of a novel G protein-coupled receptor from Burkitt's lymphoma.
PMID: 7639692 by Barella L., et al. Sequence variation of a novel heptahelical leucocyte receptor through alternative transcript formation.