This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Dapper homolog 2 Antibodies
AND DACT2 ELISA kits, Dapper homolog 2 Proteins
Many biological assays use antibodies to detect Dapper homolog 2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Dapper homolog 2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Dapper homolog 2 antibodies...
Designing an IHC experiment for Dapper homolog 2? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the DACT2 IHC GuideDACT2 Infographic by Boster Bio
All DACT2 Products
Product
Figures
Specificity
Applications
Price
DACT2 Overview
Facts about Dapper homolog 2.
Dapper homolog 2 (DACT2)
Involved in regulation of intracellular signaling pathways during evolution. Negatively regulates the Nodal signaling pathway, possibly by promoting the lysosomal degradation of Nodal receptors, for example TGFBR1.
May be involved in control of the morphogenetic behavior of kidney ureteric bud cells by keeping cells epithelial and restraining their mesenchymal character. May play an inhibitory role in the re-epithelialization of skin wounds by attenuating TGF-beta signaling (By similarity).
Gene Information
| Human | |
|---|---|
| Gene Name: | DACT2 |
| Uniprot: | Q5SW24 |
| Entrez: | 168002 |
Family
| Belongs to: |
|---|
| dapper family |
Alternative Names
bA503C24.7; C6orf116; chromosome 6 open reading frame 116; dapper homolog 2; dapper homolog 2, antagonist of beta-catenin (xenopus); dapper homolog 2, antagonist of beta-catenin; dapper, antagonist of beta-catenin, homolog 2 (Xenopus laevis); DAPPER2; DPR2; FLJ31232; MGC133141; MGC133142; RP11-503C24.7
Molecular Weight
Mass (kDA):
82.7 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 6q27 |
| Sequence: | 6; NC_000006.12 (168292830..168319777, complement) |
Diseases
- Carcinogenesis
- Malignant Neoplasms
- Neoplasms
- Sclerosis
- Disease Of Adrenal Medulla
- Colonic Neoplasms
- Endometrial Adenocarcinoma
- Parathyroid Neoplasms
- Thyroid Diseases
- Endometrial Polyp
- Dentin Dysplasia
- Diffuse Scleroderma
- Dysplasia
Pathways
- Regeneration
- Tissue Regeneration
- Odontogenesis
- Segmentation
- Notochord Formation
- Localization
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DACT2
bosterbio.com/bosterbio-gene-info-cards/DACT2
References
PMID: 15498874 by Wan D., et al. Large-scale cDNA transfection screening for genes related to cancer development and progression.
PMID: 14574404 by Mungall A.J., et al. The DNA sequence and analysis of human chromosome 6.