This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
DDC Antibodies
AND DDC ELISA kits, DDC Proteins
Many biological assays use antibodies to detect DDC, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with DDC in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop DDC antibodies...
Designing a Western blot for DDC? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the DDC Western Blot GuideDesigning an IHC experiment for DDC? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the DDC IHC GuideDDC Infographic by Boster Bio
All DDC Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IP, IHC, WB
$370
Cat # A01374-2
100 μg/vial
Cat # A01374-2
100 μg/vial
Human, Mouse, Rat
WB
$370
Cat # M01374-1
100 μl/vial
Cat # M01374-1
100 μl/vial
Human
$960
Cat # LS001644
20 µg, 100 µg
Cat # LS001644
20 µg, 100 µg
DDC Overview
Facts about Aromatic-L-amino-acid decarboxylase.
Aromatic-L-amino-acid decarboxylase (DDC)
Catalyzes the decarboxylation of L-3,4- dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. .
Gene Information
| Human | |
|---|---|
| Gene Name: | DDC |
| Uniprot: | P20711 |
| Entrez: | 1644 |
Family
| Belongs to: |
|---|
| group II decarboxylase family |
Alternative Names
AADC; AADCaromatic-L-amino-acid decarboxylase; DDC; dopa decarboxylase (aromatic L-amino acid decarboxylase); Dopa Decarboxylase; EC 4.1.1; EC 4.1.1.28
Molecular Weight
Mass (kDA):
53.926 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 7p12.2-p12.1 |
| Sequence: | 7; NC_000007.14 (50458436..50565460, complement) |
Diseases
- Neoplasms
- Malignant Neoplasms
- Nervousness
- Parkinson Disease
- Hiv Infections
- Carcinoma
- Disorders Of Porphyrin Metabolism
- Liver Diseases
- Immunologic Deficiency Syndromes
- Acquired Immunodeficiency Syndrome
- Injury To Liver
- Pituitary Diseases
- Malignant Neoplasm Of Lung
Interacting Proteins
- AR
Pathways
- Secretion
- Cell Proliferation
- Pathogenesis
- Excretion
- Transport
- Cell Death
- Regeneration
- Pigmentation
- Methylation
- Cell Growth
- Eclosion
- Immune Response
- Localization
PTMs
- Decarboxylation
- Phosphorylation
- Oxidation
- Reduction
- Methylation
- Hydroxylation
- Ubiquitination
- Amidation
- Cleavage
Research Areas
- Neuroscience
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DDC
bosterbio.com/bosterbio-gene-info-cards/DDC
References
PMID: 2590185 by Ichinose H., et al. Isolation and characterization of a cDNA clone encoding human aromatic L-amino acid decarboxylase.
PMID: 1612608 by Scherer L.J., et al. Human dopa decarboxylase: localization to human chromosome 7p11 and characterization of hepatic cDNAs.