- Table of Contents
Is involved in a number of steps of gene expression, such as transcription, mRNA maturation, mRNA export and translation. However, the specific mechanisms are not known and some functions may be specific for a subset of mRNAs.
|DEAD box helicase family|
|Sequence:||X; NC_000023.11 (41333308..41364472)|
Cell membrane. Nucleus. Cytoplasm. Cytoplasm, Stress granule. Inflammasome. Cell projection, lamellipodium. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Shuttles between the nucleus and the cytosol (PubMed:15507209, PubMed:18636090, PubMed:29899501). Exported from the nucleus partly through the XPO1/CRM1 system and partly through NXF1/TAP (PubMed:15507209, PubMed:18636090, PubMed:18596238). Localizes to nuclear pores on the outer side of the nuclear membrane (PubMed:15507209). In the cytosol, partly colocalizes with mitochondria (PubMed:20127681). At G0, predominantly lo