This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Designing a Western blot for DDX3X? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the DDX3X Western Blot GuideFacts about ATP-dependent RNA helicase DDX3X.
Is involved in a number of steps of gene expression, such as transcription, mRNA maturation, mRNA export and translation. However, the specific mechanisms are not known and some functions may be specific for a subset of mRNAs.
| Human | |
|---|---|
| Gene Name: | DDX3X |
| Uniprot: | O00571 |
| Entrez: | 1654 |

| Belongs to: |
|---|
| DEAD box helicase family |

DBXCAP-Rf; DDX14; DDX3DEAD/H box-3; DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked; DEAD box protein 3, X-chromosomal; DEAD box, X isoform; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3; EC 3.6.1; EC 3.6.4.13; helicase like protein 2; Helicase-like protein 2; HLP2ATP-dependent RNA helicase DDX3X
Mass (kDA):
73.243 kDA

| Human | |
|---|---|
| Location: | Xp11.4 |
| Sequence: | X; NC_000023.11 (41333308..41364472) |
Cell membrane. Nucleus. Cytoplasm. Cytoplasm, Stress granule. Inflammasome. Cell projection, lamellipodium. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Shuttles between the nucleus and the cytosol (PubMed:15507209, PubMed:18636090, PubMed:29899501). Exported from the nucleus partly through the XPO1/CRM1 system and partly through NXF1/TAP (PubMed:15507209, PubMed:18636090, PubMed:18596238). Localizes to nuclear pores on the outer side of the nuclear membrane (PubMed:15507209). In the cytosol, partly colocalizes with mitochondria (PubMed:20127681). At G0, predominantly lo






PMID: 10329544 by Owsianka A.M., et al. Hepatitis C virus core protein interacts with a human DEAD box protein DDX3.
PMID: 9381176 by Lahn B.T., et al. Functional coherence of the human Y chromosome.